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The role of matrix stiffness in regulating cell behaviorâ€
Hepatology, 2008Matrix stiffness (resistance to deformation), one of the many mechanical forces acting on cells, is increasingly appreciated as an important mediator of cell behavior. It regulates cell signaling broadly, with effects on growth, survival, and motility. Although the stiffness optima for different kinds of adherent cells vary widely, it is generally true
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Assembling the System Stiffness Matrix
2016Having decomposed the structures into nodes and elements, it is clear that knowing the nodal displacements will give us the internal loads in the elements. The displacements at the closed degrees of freedom are known, but we must still compute the displacements at the open degrees of freedom.
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The stiffness of extracellular matrix in regulating cellular metabolism
American Journal of Physiology-Cell PhysiologyCells interact dynamically with the extracellular matrix (ECM), which provides both structural support and biochemical signals that regulate various cellular processes. Among these, the mechanical properties of the ECM, particularly stiffness, play a crucial role in governing cell differentiation, migration, and survival.
Boyang Zha, Chunlei Zhang, Congying Wu
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A Stiffness Matrix for the Analysis of Thin Plates in Bending
Journal of the Aerospace Sciences, 1961A stiffness matrix is developed for an isotropic rectangular plate panel of uniform thickness for application to the analysis of thin plates of variable thickness in bending. The convergence characteristics of this matrix are demonstrated on simple problems with known exact, analog, and experimental solutions.
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Matrix stiffness-driven cancer progression and the targeted therapeutic strategy
Mechanobiology in Medicine, 2023Guanbin Song
exaly
Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors
Cancers, 2022Hisashi Haga, Seiichiro Ishihara
exaly

