Results 11 to 20 of about 31,588 (256)

Advances in Stigmasterol on its anti-tumor effect and mechanism of action

Frontiers in Oncology, 2022
Stigmasterol is a phytosterol derived from multiple herbaceous plants such as herbs, soybean and tobacco, and it has received much attention for its various pharmacological effects including anti-inflammation, anti-diabetes, anti-oxidization, and ...
Xiaoyu Zhang, Jiayun Wang, Lin Zhu, Xuezhen Wang, Feifei Meng, Lei Xia, Hairong Zhang   +6 more
doaj   +2 more sources

In vitro cytotoxic effect of stigmasterol derivatives against breast cancer cells

BMC Complementary Medicine and Therapies, 2023
Background Stigmasterol is an unsaturated phytosterol that belong to the class of tetracyclic steroids abundant in Rhoicissus tridentata. Stigmasterol is an important constituent since it has shown impressive pharmacological effects such as anti ...
Nondumiso Premilla Dube, Vuyelwa Jacqueline Tembu, Getrude R Nyemba, Candace Davison, Goitsemodimo Herckious Rakodi, Douglas Kemboi, Jo-Anne de la Mare, Xavier Siwe-Noundou, Amanda-Lee Ezra Manicum   +8 more
doaj   +2 more sources

Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis

Frontiers in Immunology, 2021
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with gut microbiota disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol, a plant-derived sterol, has shown anti-inflammatory effects. Our study aimed
Shuting Wen, Long He, Zhuotai Zhong, Runyuan Zhao, Senhui Weng, Hong Mi, Fengbin Liu, Fengbin Liu, Fengbin Liu   +8 more
doaj   +2 more sources

Antimicrobial Activities of Stigmasterol from Piper crocatum In Vitro and In Silico

Journal of Chemistry
The high incidence of oral health issues and antibiotic resistance has stimulated research into discovering novel antimicrobial drugs. Prior evidence suggests that red betel leaves (Piper crocatum Ruiz and Pav) possess potential antimicrobial properties,
Seftiana Lestari, Dikdik Kurnia, Tri Mayanti, Leny Heliawati   +3 more
doaj   +2 more sources

Research Progress on the Therapeutic Mechanisms of Stigmasterol for Multiple Diseases

Molecules
Stigmasterol is a plant-derived phytosterol that has attracted considerable attention because of its diverse biological activities and potential therapeutic applications.
Juan Li, Xinhua Zheng, Jinxu Qi
doaj   +2 more sources

Comparative effects of dietary stigmasterol and oxidised stigmasterol on cholesterol absorption and metabolism in mice. [PDF]

Br J Nutr
Abstract Dietary phytosterols exert hypocholesterolemic effects by inhibiting cholesterol absorption in the small intestine. However, oxidised phytosterols exert harmful effects. In this study, we compared the effects of dietary stigmasterol or oxidised stigmasterol (OS) on cholesterol absorption and metabolism in
Ohara Y, Osada K.
europepmc   +4 more sources

Maize Zmcyp710a8 Mutant as a Tool to Decipher the Function of Stigmasterol in Plant Metabolism

Frontiers in Plant Science, 2021
Sterols are integral components of membrane lipid bilayers in eukaryotic organisms and serve as precursors to steroid hormones in vertebrates and brassinosteroids (BR) in plants.
Siddique I. Aboobucker, Lucas J. Showman, Thomas Lübberstedt, Walter P. Suza   +3 more
doaj   +1 more source

­­­­Evaluation of Design and Fabrication of Food-Grade Nanofibers from Chitosan-Gelatin for Nanoencapsulation of Stigmasterol Using the Electrospinning Method [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: In this research, electrospinning method was employed to fabricate food-grade nanofibers (NFs) from chitosan-gelatin combination for stigmasterol encapsulation.
Mir-Michael Mousavi, Mohammadali Torbati, Parastou Farshi, Hedayat Hosseini, Masoud Aman Mohammadi, Seyede Marzieh Hosseini, Simzar Hosseinzadeh   +6 more
doaj   +1 more source

Foliar Spray of Stigmasterol Regulates Physiological Processes and Antioxidant Mechanisms to Improve Yield and Quality of Sunflower Under Drought Stress

Journal of soil science and plant nutrition, 2023
Drought stress is an unavoidable challenge limiting plant production and quality. Stigmasterol is a potential compound for plant protection and improvement productivity under drought.
R. S. Hanafy, M. S. Sadak
semanticscholar   +1 more source

Stigmasterol Protects Against Steatohepatitis Induced by High-Fat and High-Cholesterol Diet in Mice by Enhancing the Alternative Bile Acid Synthesis Pathway.

Journal of NutriLife, 2023
BACKGROUND Hepatic cholesterol accumulation is a significant risk factor in the progression of non-alcoholic fatty liver disease (NAFLD) to steatohepatitis.
Yan Xin, Xiang Li, Xuan Zhu, Xiaozhuan Lin, Mengliu Luo, Yunjun Xiao, Yongdui Ruan, Honghui Guo   +7 more
semanticscholar   +1 more source