Results 191 to 200 of about 31,144 (246)

Network pharmacology and molecular docking reveal the mechanism of Zishen Yutai Wan against polycystic ovary syndrome. [PDF]

J Ovarian Res
Ying Z, Hongqiu Z, Junjie L, Peijuan W, Qian Z, Mengxue D, Yan L.   +6 more
europepmc   +1 more source

Correction to "Metabolomics of the Protective Effect of <i>Ampelopsis grossedentata</i> and Its Major Active Compound Dihydromyricetin on the Liver of High-Fat Diet Hamster". [PDF]

Evid Based Complement Alternat Med
europepmc   +1 more source

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Stigmasterol attenuates inflammatory response of microglia via NF-κB and NLRP3 signaling by AMPK activation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Although its pathogenesis remains unclear, studies have indicated microglia-mediated neuroinflammation playing an important role.
Fan Jie, Xuan Yang, Bowen Yang, Yan Liu, Lipeng Wu, Baiyi Lu   +5 more
semanticscholar   +1 more source

Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF‐κB pathway to alleviate neuropathic pain

Phytotherapy Research, 2023
(Switching from the microglial M1 phenotype to the M2 phenotype is a promising therapeutic strategy for neuropathic pain (NP). This study aimed to investigate the potential use of stigmasterol for treating NP.
Waimei Si, Xin Li, Bei Jing, Shiquan Chang, Yachun Zheng, Zhenni Chen, Guoping Zhao, Di Zhang   +7 more
semanticscholar   +1 more source

Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma.

Phytomedicine, 2023
BACKGROUND Hepatocellular carcinoma (HCC), the most primary malignant liver tumor and is ranked as the fifth most common malignancy worldwide. Despite various therapeutic approaches being used in clinical practice, the overall effectiveness remains ...
Ran Huo, Wenjing Yang, Yu Liu, Te Liu, Tong Li, Chuyu Wang, Bai-Shen Pan, Bei-Li Wang, Wei Guo   +8 more
semanticscholar   +1 more source

Absolute configuration assignment of stigmasterol oxiranes

Chirality, 2021
AbstractDiastereoisomeric stigmasterol oxiranes 4, 5, 8, and 9 are known phytosterol oxidation products (POPs) that have been evaluated for their cytotoxicity, although the results are of limited significance since, in most cases, they were evaluated as mixtures.
Miguel Á. Fuentes‐Figueroa, Pedro Joseph‐Nathan, Eleuterio Burgueño‐Tapia   +2 more
openaire   +2 more sources

A Comprehensive Update on Phytochemistry, Analytical Aspects, Medicinal Attributes, Specifications and Stability of Stigmasterol.

Steroids, 2023
Phytosterols are bioactive substances naturally found in plant cell membranes, and their chemical structure is comparable to cholesterol found in mammalian cells.
Megha Goswami, Priya, S. Jaswal, G. Gupta, Sant Kumar Verma   +4 more
semanticscholar   +1 more source

Molecular dynamics study of stigmasterol and beta-sitosterol of Morinda citrifolia L. towards α-amylase and α-glucosidase

Journal of Biomolecular Structure and Dynamics, 2023
Previous in vivo studies of Morinda citrifolia (Rubiaceae) reported that the extract inhibited α-amylase and reduced blood glucose levels in streptozotocin-induced diabetes mice.
N. Lolok, Adi Sumiwi, Dwi Syah, Fitra Ramadhan, J. Levita, I. Sahidin   +5 more
semanticscholar   +1 more source