Results 111 to 120 of about 45,125 (278)

Acute and sub-chronic toxicity of Cajanus cajan leaf extracts

open access: yesPharmaceutical Biology, 2017
Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts.
Rong Tang   +5 more
doaj   +1 more source

Preliminary Results on Contents of Resveratrol in Wine of Organic and Conventional Vineyards [PDF]

open access: yes, 2000
Phytoalexins are compounds synthesised by plants in response to various stresses. In grapevines, these compounds belong to the stilbene family. Several studies have shown that resveratrol is usually triggered by infection of berries by Botrytis cinerea ...
Adrian, M., Lévite, D., Tamm, L.
core  

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

1,4-Pentanediol as an Alternative Biomass-Derived Medium for the Phosphine-Free Heck Coupling Reactions. [PDF]

open access: yesChemSusChem
In this research, a phosphine‐free Heck coupling reaction was performed using biomass‐derived 1,4‐pentanediol and a polar protic solvent. It was demonstrated that a wide scope of products could be isolated by a simple filtration, eliminating the high‐solvent‐consuming column chromatography and reducing the E‐factor by more than 90% compared to ...
Árvai C, Mika LT.
europepmc   +2 more sources

Picosecond-jet spectroscopy and photochemistry. Energy redistribution and its impact on coherence, isomerization, dissociation and solvation [PDF]

open access: yes, 1983
The development of the picosecond-jet technique is presented. The applications of the technique to the studies of coherence (quantum beats), photodissociation, isomerization and partial solvation of molecules in supersonic-jet beams are detailed with ...
Zewail, Ahmed H.
core  

Aggregation‐induced enhanced emission for quantification of recycled content in automotive plastics

open access: yesPolymer International, EarlyView.
Quantifying recycled content in four automotive plastics using aggregation‐induced enhanced emission showed that performance was highly dependent on both polymer and additive chemistries. Abstract The use of plastics in the automotive industry is increasing due to their versatility, light weight and affordability.
Saleh S Soomro   +2 more
wiley   +1 more source

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo   +3 more
wiley   +1 more source

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Characterizing Subcritical Assemblies with Time of Flight Fixed by Energy Estimation Distributions

open access: yes, 2018
We present the Time of Flight Fixed by Energy Estimation (TOFFEE) as a measure of the fission chain dynamics in subcritical assemblies. TOFFEE is the time between correlated gamma rays and neutrons, subtracted by the estimated travel time of the incident
Marleau, Peter   +2 more
core   +1 more source

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