Piceatannol as a potential antiviral agent against vaccinia virus at multiple stages [PDF]
Frontiers in MicrobiologyThe resurgence of mpox, caused by the mpox virus (MPXV), has intensified the demand for effective antiviral agents. This study evaluates the antiviral activity of piceatannol, a natural polyphenol, utilizing vaccinia virus (VACV) as a model due to the ...
Liyuan Zhang +6 more
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Plants, 2021 Resveratrol (3,4′,5-trans-trihydroxystilbene) and piceatannol (3,3′,4′,5-trans-tetraphydroxystilbene) are major stilbene compounds that are predominantly present in various natural foods, such as berries and fruits.
In Sil Park +4 more
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Oral supplementation with piceatannol improves skin hydration and reduces wrinkle severity: a randomized, double-blind, placebo-controlled trial [PDF]
Frontiers in NutritionBackground/objectivesThe skin is the largest organ of the human body and undergoes age-related changes, such as reduced hydration, loss of elasticity, and wrinkle formation, which can affect appearance and quality of life. Piceatannol has antioxidant and
Yosuke Seto +10 more
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Molecules, 2020 Piceatannol is also named as trans-3,4,3′,5′-tetrahydroxy-stilbene, which is a natural analog of resveratrol and a polyphenol existing in red wine, grape and sugar cane.
Wei-Hui Hu +6 more
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Piceatannol attenuates thoracic aortic aneurysm progression by targeting STK33 [PDF]
Biology DirectBackground Thoracic aortic aneurysm (TAA) is a life-threatening vascular condition with limitedpharmacological interventions. This study aimed to identify novel causaldruggable genes and therapeutic candidates for TAA.
Yubo Liu +3 more
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Integrated protein and metabolic engineering enable high-yield biosynthesis of resveratrol derivatives in Yarrowia lipolytica [PDF]
Synthetic and Systems BiotechnologyPiceatannol and pterostilbene, two resveratrol derivatives with superior pharmacological properties, hold significant promise for therapeutic and nutraceutical applications.
Yuanqing Wu +5 more
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Integrating network pharmacology, molecular docking and experimental verification to explore the therapeutic effect of piceatannol on rheumatoid arthritis [PDF]
Frontiers in ImmunologyObjectivePiceatannol (PIC) exhibits antioxidant and anti-inflammatory activities. This study integrates network pharmacology and experimental validation to investigate its potential role in rheumatoid arthritis (RA).MethodsPIC targets were predicted ...
Mingyi Yang +18 more
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Passion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells [PDF]
Scientific ReportsAge-related macular degeneration (AMD) is a major cause of vision loss among adults. We investigated the protective effects of passion fruit seed extract (PFSE) and its rich polyphenol piceatannol in an AMD cell model in which human retinal pigment ...
Haruka Uozumi +4 more
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The anti-Toxoplasma activity of the plant natural phenolic compound piceatannol
Frontiers in Veterinary Science, 2022 Toxoplasma gondii is an obligate intracellular protozoan that infects the nucleated cells of warm-blooded animals and causes life-threatening disease in immunocompromised patients.
Yucong Jiang +3 more
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Autophagy activation by dietary piceatannol enhances the efficacy of immunogenic chemotherapy
Frontiers in Immunology, 2022 Immunogenic cell death (ICD) promotes the immune antitumor response via releasing damage-associated molecular patterns (DAMPs) from dying tumor cells. The induction of autophagy improves the efficacy of multiple immunogenic chemotherapies.
Shuang Wang +11 more
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