Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase. [PDF]
PLoS ONE, 2018 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one of the key redox-sensitive proteins whose activity is largely affected by oxidative modifications at its highly reactive cysteine residue in the enzyme's active site (Cys149).
Joanna Gerszon +5 more
doaj +3 more sources
Molecules, 2022 Dysfunction of the blood–brain barrier (BBB) is involved in the pathogenesis of many cerebral diseases. Oxidative stress and inflammation are contributing factors for BBB injury.
Yan Zhou +3 more
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Stimulation of Eryptosis, the Suicidal Erythrocyte Death by Piceatannol [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: Piceatannol, an analog and metabolite of resveratrol, is effective against various disorders including malignancy. It is in part effective by triggering suicidal death or apoptosis of tumor cells.
Elena Signoretto +2 more
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Antioxidants, 2019 Piceatannol is a resveratrol metabolite that is considered a potent antioxidant and cytoprotector because of its high capacity to chelate/sequester reactive oxygen species. In pathogenesis of periodontal diseases, the imbalance of reactive oxygen species
Flávia Póvoa da Costa +12 more
doaj +2 more sources
Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. [PDF]
PLoS ONE, 2016 Piceatannol, a resveratrol metabolite, is a phenolic compound found in red wine and grapes. We investigated the effect of piceatannol on renal fibrosis and histone deacetylase (HDAC) expression in a mouse model of unilateral ureteral obstruction (UUO ...
Sin Young Choi +9 more
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Piceatannol induced apoptosis through up-regulation of microRNA-181a in melanoma cells
Biological Research, 2017 Background Melanoma took top position among the lethal cancers and, despite there have been some great attempts made to increase the natural life of patients with metastatic disease, long-lasting and complete remissions are few.
Maotao Du, Zhong Zhang, Tao Gao
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Stability of Piceatannol in Dulbecco's Modified Eagle's Medium by In Situ UPLC-MS/MS Analysis [PDF]
Natural Product CommunicationsPiceatannol is a stilbenoid, which has shown bioactivities in various cell culture models. However, its stability in cell culture medium is not clear. Here, UPLC-MS/MS was applied in situ to analyze the degradation products of piceatannol in Dulbecco's ...
Meng S. Cheong +5 more
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In vivo evaluation of analgesic and antipyretic activities of piceatannol-rich extract from Senna garrettiana heartwood [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2017 A methanolic extract from Senna garrettiana (S. garrettiana) heartwood was prepared and then a fractionation process was performed to obtain hexane, dichloromethane, ethyl acetate, and aqueous fractions.
Suparada Surapanthanakorn +3 more
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Piceatannol as an Antiviral Inhibitor of PRV Infection In Vitro and In Vivo
Animals, 2023 Pseudorabies virus (PRV) belongs to the family Herpesviridae. PRV has a wide host range and can cause cytopathic effects (CPEs) in PK-15 cells. Therefore, PRV was used as a model to study the antiviral activity of piceatannol.
Zhiying Wang +6 more
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Characterization of Grape Cane Stilbenoids and Their Photo-Degradation Products by HPLC-DAD Coupled With Trapped Ion Mobility Spectrometry and High-Resolution Tandem Mass Spectrometry. [PDF]
Rapid Commun Mass SpectromABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Besrukow P +3 more
europepmc +2 more sources