Results 31 to 40 of about 6,601 (222)

Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells

Current Research in Food Science, 2020
Non-alcoholic fatty liver disease (NAFLD), which affects over 20% of the adult population, is the most common liver disease worldwide and can progress to inflammatory hepatitis, cirrhosis and liver cancer.
Jason Szuhao Yang, Jozxelle Tongson, Kee-Hong Kim, Yeonhwa Park   +3 more
doaj   +1 more source

In vivo evaluation of analgesic and antipyretic activities of piceatannol-rich extract from Senna garrettiana heartwood [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
A methanolic extract from Senna garrettiana (S. garrettiana) heartwood was prepared and then a fractionation process was performed to obtain hexane, dichloromethane, ethyl acetate, and aqueous fractions.
Suparada Surapanthanakorn, Narubodee Phadoongsombut, Chatchai Wattanapiromsakul, Wantana Reanmongkol   +3 more
doaj   +1 more source

Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling [PDF]

, 1983
BACKGROUND: Mantle cell lymphoma (MCL) is currently an incurable entity, and new therapeutic approaches are needed. We have applied a high-throughput phospho-proteomic technique to MCL cell lines to identify activated pathways and we have then validated ...
Chiara Pighi, Ting-Lei Gu, Irene Dalai, Stefano Barbi, Claudia Parolini, Anna Bertolaso, Serena Pedron, Alice Parisi, Jianmin Ren, Daniela Cecconi, Marco Chilosi, Fabio Menestrina, Alberto Zamò   +12 more
core   +1 more source

Novel curcumin- and emodin-related compounds identified by 2D/3D conformer screening induce apoptosis in tumor cells [PDF]

, 2005
Background Inhibition of the COP9 signalosome (CSN) associated kinases CK2 and PKD by curcumin causes stabilization of the tumor suppressor p53. It has been shown that curcumin induces tumor cell death and apoptosis.
Melanie Füllbeck, Xiaohua Huang, Renate Dumdey, Cornelius Frommel, Wolfgang Dubiel, Robert Preissner, D Bech-Otschir, S Uhle, U Marklund, A Rykx, D Bech-Otschir, D Bech-Otschir, M Seeger, M Naumann, EA Slee, B Vogelstein, E Shaulian, C Pollmann, W Henke, PJ Moos, JL Arbiser, M Thimm, X Chen, CA Lipinski, RD Snyder, R Liu, F Hoppe-Seyler, J Wesierska-Gadek, M Athanassiou, RM Elledge, T Choudhuri, WM Kast, DE Shieh, A Liontas, KM Youssef, BK Adams, I Vermes, JL Jenkins, FL Stahura, DL Graham, H Yim, S Sarno, MT Huang, X Bai, L Li   +44 more
core   +2 more sources

Piceatannol Increases Antioxidant Defense and Reduces Cell Death in Human Periodontal Ligament Fibroblast under Oxidative Stress

Antioxidants, 2019
Piceatannol is a resveratrol metabolite that is considered a potent antioxidant and cytoprotector because of its high capacity to chelate/sequester reactive oxygen species. In pathogenesis of periodontal diseases, the imbalance of reactive oxygen species
Flávia Póvoa da Costa, Bruna Puty, Lygia S. Nogueira, Geovanni Pereira Mitre, Sávio Monteiro dos Santos, Bruno José Brito Teixeira, Maria Sueli da Silva Kataoka, Manoela Domingues Martins, Carlos Augusto Galvão Barboza, Marta Chagas Monteiro, Hervé Rogez, Edivaldo Herculano Corrêa de Oliveira, Rafael Rodrigues Lima   +12 more
doaj   +1 more source

Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells

Pharmaceutics, 2021
Piceatannol (PIC) is a naturally occurring polyphenolic stilbene, and it has pleiotropic pharmacological properties. Moreover, PIC has cytotoxic actions among various cancer cells.
Nabil A. Alhakamy, Giuseppe Caruso, Mohammed W. Al-Rabia, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Hani Z. Asfour, Samah Alshehri, Sami H. Alzaharani, Meshari M. Alhamdan, Waleed Y. Rizg, Ahmed N. Allam   +10 more
doaj   +1 more source

Piceatannol induced apoptosis through up-regulation of microRNA-181a in melanoma cells

Biological Research, 2017
Background Melanoma took top position among the lethal cancers and, despite there have been some great attempts made to increase the natural life of patients with metastatic disease, long-lasting and complete remissions are few.
Maotao Du, Zhong Zhang, Tao Gao
doaj   +1 more source

The Antiproliferative Activity of Adiantum pedatum Extract and/or Piceatannol in Phenylhydrazine-Induced Colon Cancer in Male Albino Rats: The miR-145 Expression of the PI-3K/Akt/p53 and Oct4/Sox2/Nanog Pathways

Molecules, 2023
Colon cancer is one of the most common types of cancer worldwide, and its incidence is increasing. Despite advances in medical science, the treatment of colon cancer still poses a significant challenge.
Tarek Khamis, Abd Al-Aziz Abas Diab, Mansour H. Zahra, Samih Ebrahim El-Dahmy, Basant Ahmed Abd Al-Hameed, Adel Abdelkhalek, Mahmoud A. Said, Hussein Abdellatif, Liana Mihaela Fericean, Ioan Banatean-Dunea, Ahmed Hamed Arisha, Mai S. Attia   +11 more
doaj   +1 more source

CSN5 binds to misfolded CFTR and promotes its degradation [PDF]

, 2008
Cystic fibrosis is mainly caused by mutations that interfere with the biosynthetic folding of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The aim of this study was to find cellular proteins interacting with CFTR and regulating
Tanguy, Gaëlle, Drévillon, Loïc, Arous, Nicole, Hasnain, Afia, Hinzpeter, Alexandre, Fritsch, Janine, Goossens, Michel, Fanen, Pascale   +7 more
core   +1 more source

Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice

Frontiers in Pharmacology, 2022
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease characterized by myofibroblast accumulation and extracellular matrix deposition, which lead to irreversible damage of the lung’s architecture and the ...
Hanjing Sheng, Gang Lin, Shengxian Zhao, Weibin Li, Zhaolin Zhang, Weidong Zhang, Li Yun, Xiaoyang Yan, Hongyu Hu   +8 more
doaj   +1 more source