Results 31 to 40 of about 3,444 (174)
Pharmaceutics, 2021 Piceatannol (PIC) is a naturally occurring polyphenolic stilbene, and it has pleiotropic pharmacological properties. Moreover, PIC has cytotoxic actions among various cancer cells.
Nabil A. Alhakamy +10 more
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Molecules, 2023 Colon cancer is one of the most common types of cancer worldwide, and its incidence is increasing. Despite advances in medical science, the treatment of colon cancer still poses a significant challenge.
Tarek Khamis +11 more
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Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice
Frontiers in Pharmacology, 2022 Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease characterized by myofibroblast accumulation and extracellular matrix deposition, which lead to irreversible damage of the lung’s architecture and the ...
Hanjing Sheng +8 more
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Biomedicines, 2023 Oxidative stress and epigenetic alterations, including the overexpression of all class I and II histone deacetylases (HDACs), particularly HDAC2 and HDAC4, have been identified as key molecular mechanisms driving pulmonary fibrosis.
Nehal Ezz Eldeen +4 more
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Piceatannol Inhibits Melanogenesis by Its Antioxidative Actions
Biological and Pharmaceutical Bulletin, 2007 In our efforts to find new skin lightening agents, piceatannol (PICE) was investigated for its antioxidative property and ability to inhibit melanogenesis. In this study, PICE's effect on inhibition of mushroom tyrosinase, and tyrosinase inhibiting activity and melanin content were assessed utilizing the B16F10 melanoma cell (B16 cell) culture system ...
Yokozawa, Takako, Kim, You Jung
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Clinical and Translational Medicine, 2021 Inflammatory bowel disease (IBD) has emerged a global disease and the ascending incidence and prevalence is accompanied by elevated morbidity, mortality, and substantial healthcare system costs.
Wenbin Gong +12 more
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The occurrence of the stilbene piceatannol in grapes
, 2002 Piceatannol (trans-3,3',4,5'-tetrahydroxy-stilbene) is a natural stilbene occurring in a number of plant species, and it has been shown to have beneficial effects on human health. The compound can seldom be consumed by humans, because it occurs in non-food plants, or in non-edible organs.
Bavaresco, L. +5 more
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Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption by suppressing MAPK, NF-κB and AKT signalling pathways and promotes Caspase3-mediated apoptosis of mature osteoclasts [PDF]
Royal Society Open Science, 2019 Osteoclasts are multinuclear giant cells that have unique ability to degrade bone. The search for new medicines that modulate the formation and function of osteoclasts is a potential approach for treating osteoclast-related bone diseases.
Liuliu Yan +4 more
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Micromachines, 2021 Chemotherapy has led to many undesirable side effects, as these are toxic drugs that are unable to differentiate between cancer and normal cells. Polyphenols (tea catechins) are an ideal option as alternative chemotherapeutics owing to their inherent ...
Mingyan Guo +3 more
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Molecules, 2021 Synthetic arylamines and dietary phytophenolics could inhibit ferroptosis, a recently discovered regulated cell death process. However, no study indicates whether their inhibitory mechanisms are inherently different.
Ban Chen +5 more
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