Results 1 to 10 of about 40,978 (244)
Functional Role of STIM-1 and Orai1 in Human Microvascular Aging [PDF]
Cells, 2022 The impact of aging on vascular function is heterogeneous depending on the vascular territories. Calcium regulation plays a key role in vascular function and has been implicated in aging-related hypercontractility of corpus cavernosum.
Javier Romero-Otero +2 more
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Mechanism of STIM activation [PDF]
Current Opinion in Physiology, 2020 Store-operated calcium entry (SOCE) through Orai ion channels is an intracellular signaling pathway that is initiated by ligand-induced depletion of calcium from the endoplasmic reticulum (ER) store. The molecular link between SOCE and ER store depletion is thereby provided by a distinct class of single pass ER transmembrane proteins known as stromal ...
Fahrner, Marc +2 more
openaire +4 more sources
, 2014 This thesis documents specific relationships I observe and have with individuals living with autism. Through an extensive interview and interactive process, the varied interactions furthered my understanding of these individuals and spurred my desire to construct a visual representation of them and their personalities apart from a medical diagnosis. As
John Wilson (539832)
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STIM Proteins: An Ever-Expanding Family [PDF]
International Journal of Molecular Sciences, 2020 Stromal interaction molecules (STIM) are a distinct class of ubiquitously expressed single-pass transmembrane proteins in the endoplasmic reticulum (ER) membrane. Together with Orai ion channels in the plasma membrane (PM), they form the molecular basis of the calcium release-activated calcium (CRAC) channel. An intracellular signaling pathway known as
Herwig Grabmayr +2 more
openaire +5 more sources
Unlocking the roles of plasma soluble T-cell immunoglobulin and mucin domain-containing protein 3 in kidney diseases: findings from native and allograft biopsy cohorts [PDF]
Molecular BiomedicineChronic kidney disease (CKD) and renal allograft failure represent escalating global health burdens characterized by progressive tissue remodeling. Although interstitial fibrosis and tubular atrophy (IF/TA) are the primary determinants of long-term ...
Yamei Li +16 more
doaj +2 more sources
Moving Image Review & Art Journal (MIRAJ), TheSTIM CINEMA is a multiscreen gallery installation co-created by Steven Eastwood and the Neurocultures Collective and curated by Gilly ...
Lucy Walker +6 more
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Elevated high sensitivity cardiac troponin T among men with HIV who use stimulants: A cross-sectional study of subclinical cardiovascular injury. [PDF]
PLoS ONEPeople with HIV (PWH) experience elevated cardiovascular disease risk compared to people without HIV. Stimulant use may further increase subclinical myocardial injury among PWH, but data on cardiovascular biomarkers, including serum high-sensitivity ...
Michaela E Larson +10 more
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Soluble TIM-3 and galectin-9 predict survival in gastric and gastroesophageal junction cancer [PDF]
iScienceSummary: Current biomarkers for diagnosis and prognosis prediction in gastric cancer (GC) and gastroesophageal junction (GEJ) cancer have limited accuracy, and the role of soluble immune checkpoints is unknown.
David Digomann +20 more
doaj +2 more sources
Stim: a fast stabilizer circuit simulator [PDF]
Quantum, 2021 This paper presents “Stim", a fast simulator for quantum stabilizer circuits. The paper explains how Stim works and compares it to existing tools. With no foreknowledge, Stim can analyze a distance 100 surface code circuit (20 thousand qubits, 8 million ...
Craig Gidney
doaj +1 more source
TIM-4 Regulates Allergic Airway Inflammation and Mast Cell Activation by Binding to CD300b [PDF]
Journal of Asthma and AllergyYuki Tanabe,1,2 Fumitaka Kamachi,1 Jun Ito,2 Norihiro Harada,2 Sonoko Harada,2,3 Fumihiko Makino,2 Yoshiyuki Abe,4 Nobuhiro Nakano,3 Kumi Izawa,3 Francois Niyonsaba,3 Chiharu Nishiyama,5 Jiro Kitaura,3 Ko Okumura,1,3 Kazuhisa Takahashi,2 Hisaya Akiba,1 ...
Tanabe Y +15 more
doaj +2 more sources