Results 31 to 40 of about 43,138 (232)

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange   +8 more
wiley   +1 more source

Soluble Immune Checkpoints and Anti-HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function. [PDF]

open access: yesImmunology
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Pehlivanoğlu C   +8 more
europepmc   +2 more sources

Transcut stim autonomic: data dictionary

open access: yes, 2023
Data dictionary for file: Transcut stim ...
Solinsky, Ryan
core   +1 more source

Safety and efficacy of electrical stimulation for lower-extremity muscle weakness in intensive care unit 2019 Novel Coronavirus patients: A phase I double-blinded randomized controlled trial

open access: yesFrontiers in Medicine, 2022
BackgroundIntensive care unit (ICU) prolonged immobilization may lead to lower-extremity muscle deconditioning among critically ill patients, particularly more accentuated in those with 2019 Novel Coronavirus (COVID-19) infection. Electrical stimulation (
Alejandro Zulbaran-Rojas   +8 more
doaj   +1 more source

The STIM/Orai coupling machinery [PDF]

open access: yesChannels, 2008
Calcium (Ca(2+)) entry into non-excitable cells is mainly carried by store-operated channels (SOCs), which serve essential functions ranging from regulation of transcription to cell growth. The best-characterized store-operated current, I(CRAC), is the calcium release-activated calcium (CRAC) current initially discovered in T-lymphocytes and mast cells.
Irene, Frischauf   +5 more
openaire   +2 more sources

A qualitative exploration of participant experiences of using Alpha-Stim AID for the treatment of moderate severity depressive symptoms in primary care

open access: yesPsychiatry Research Communications, 2023
Background: Alpha-Stim AID is a device for the treatment of anxiety, insomnia and depression. Evidence on patient experiences of using the device for depressive symptoms is scarce.
Priya Patel   +7 more
doaj   +1 more source

Unlocking SOAR releases STIM [PDF]

open access: yesThe EMBO Journal, 2011
A crucial component of the receptor-evoked Ca(2+) signal is Ca(2+) influx mediated by the store-operated Ca(2+) channels (SOCs). The molecular makeup of one SOC is the endoplasmic reticulum (ER) Ca(2+) sensor STIM1 and the pore-forming Orai1. Ca(2+) release from the ER leads to co-clustering of STIM1 and Orai1 to activate Orai1.
Joo Young, Kim, Shmuel, Muallem
openaire   +3 more sources

Carandoom/STIM-ORAI-Segmentation:

open access: yes, 2021
No description ...
Christopher Henry
core   +1 more source

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2018
Mediated through the combined action of STIM proteins and Orai channels, store-operated Ca2+ entry (SOCE) functions ubiquitously among different cell types. The existence of multiple STIM and Orai genes has made it difficult to assign specific roles of each STIM and Orai homolog in mediating Ca2+ signals.
Sisi Zheng   +15 more
openaire   +2 more sources

The Ca2+ Sensor STIM in Human Diseases

open access: yes, 2023
The STIM family of proteins plays a crucial role in a plethora of cellular functions through the regulation of store-operated Ca2+ entry (SOCE) and, thus, intracellular calcium homeostasis.
Nieto-Felipe, Joel   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy