Results 41 to 50 of about 40,978 (244)
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange +8 more
wiley +1 more source
Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines [PDF]
Pflügers Archiv - European Journal of Physiology, 2018 Mediated through the combined action of STIM proteins and Orai channels, store-operated Ca2+ entry (SOCE) functions ubiquitously among different cell types. The existence of multiple STIM and Orai genes has made it difficult to assign specific roles of each STIM and Orai homolog in mediating Ca2+ signals.
Sisi Zheng +15 more
openaire +2 more sources
Dissecting the mechanism of STIM coupling to Orai [PDF]
, 2011 Store-operated Ca2+ entry (SOCE) triggered by the depletion of endoplasmic reticulum (ER) luminal Ca2+ stores is a major Ca2+ entry pathway in non-excitable cells and is essential in physiological Ca2+ signaling and homeostasis. STIM proteins are sensors
Deng, Xiaoxiang
core +1 more source
The experience of using Alpha-Stim AID cranial electrotherapy stimulation (CES) for symptoms of anxiety [PDF]
, 2023 As accepted for publication© 2023 Griffiths C et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Jiang, Harmony +2 more
core +1 more source
Emotions and Values in Live Shopping: Uncovering the Role of PAD Model and Flow Experience
Gadjah Mada International Journal of BusinessMarketing via social media has fast communication and diverse consumers. The research applies the Pleasure-Arousal Dominance (PAD) Model to show the influence of pleasure to explain the influence of stimulation on a person's behavioral intentions ...
alivia meyrizka utami +1 more
doaj +1 more source
Level of serum soluble Tim-3 expression in early-phase acute pancreatitis
The Turkish Journal of Gastroenterology, 2019 Background/Aims: T-cell immunoglobulin and mucin domain 3 (Tim-3) assumedly play a crucial immunomodulatory role in inflammatory response. Data on the potential role of soluble Tim-3 (sTim-3) in acute pancreatitis (AP) are scarce.
Min Lin +4 more
doaj +1 more source
Advanced Science, EarlyView.The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis +32 more
wiley +1 more source
Nuclear magnetic resonance microimaging of mouse spinal cord in vivo
Neurobiology of Disease, 2004 The spinal cord is the site of traumatic injuries, the devastating consequences of which constitute a public health problem in our societies. So far, there is no efficient repair therapeutic approach, and this is mainly due to the great difficulty for ...
Jean-Marie Bonny +5 more
doaj +1 more source
Advanced Science, EarlyView.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Cross-linking of Orai1 channels by STIM proteins [PDF]
, 2018 Significance The work presents a unique understanding of the organization and function of two ubiquitously expressed proteins, central in generating calcium signals in all cell types. These are the intracellular calcium sensing “STIM” proteins,
Ping Xin +9 more
core +1 more source