Results 41 to 50 of about 43,138 (232)

Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial [PDF]

open access: yes, 2023
Background: Randomised sham-controlled trials of cranial electrostimulation with the Alpha-Stim Anxiety Insomnia and Depression (AID) device have reported improved anxiety and depression symptoms; however, no adequately powered sham-controlled trials in ...
Nixon, Neil   +17 more
core   +3 more sources

Emotions and Values in Live Shopping: Uncovering the Role of PAD Model and Flow Experience

open access: yesGadjah Mada International Journal of Business
Marketing via social media has fast communication and diverse consumers. The research applies the Pleasure-Arousal Dominance (PAD) Model to show the influence of pleasure to explain the influence of stimulation on a person's behavioral intentions ...
alivia meyrizka utami   +1 more
doaj   +1 more source

The Role of T-cell Immunoglobulin and Mucin Domain-Containing Molecule-3 as Disease Activity Marker in Systemic Lupus Erythematosus [PDF]

open access: yesZagazig University Medical Journal
Background: Systemic lupus erythematosus (SLE) is an example of a systemic autoimmune illness. Although the T cell immunoglobulin and mucin domain (TIM) family is linked to autoimmune disorders, it is yet unknown how much of this family is expressed in ...
Lobna kotb   +4 more
doaj   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Nuclear magnetic resonance microimaging of mouse spinal cord in vivo

open access: yesNeurobiology of Disease, 2004
The spinal cord is the site of traumatic injuries, the devastating consequences of which constitute a public health problem in our societies. So far, there is no efficient repair therapeutic approach, and this is mainly due to the great difficulty for ...
Jean-Marie Bonny   +5 more
doaj   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Level of serum soluble Tim-3 expression in early-phase acute pancreatitis

open access: yesThe Turkish Journal of Gastroenterology, 2019
Background/Aims: T-cell immunoglobulin and mucin domain 3 (Tim-3) assumedly play a crucial immunomodulatory role in inflammatory response. Data on the potential role of soluble Tim-3 (sTim-3) in acute pancreatitis (AP) are scarce.
Min Lin   +4 more
doaj   +1 more source

Dissecting the mechanism of STIM coupling to Orai [PDF]

open access: yes, 2011
Store-operated Ca2+ entry (SOCE) triggered by the depletion of endoplasmic reticulum (ER) luminal Ca2+ stores is a major Ca2+ entry pathway in non-excitable cells and is essential in physiological Ca2+ signaling and homeostasis. STIM proteins are sensors
Deng, Xiaoxiang
core   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

open access: yesAdvanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu   +4 more
wiley   +1 more source

Transcut stim autonomic

open access: yes, 2023
Blood pressure, R-R interval, and popliteal blood flow for controls and participants with spinal cord injuries. Baseline and at 80% motor-threshold using 120Hz, 30Hz, 30Hz+5kHz carrier frequencies at T10-T11.
Solinsky, Ryan
core   +1 more source

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