Results 51 to 60 of about 43,138 (232)
Sonoselective Transfection of Glioma Endothelium
Advanced Science, EarlyView.Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski +8 more
wiley +1 more source
Chinese Journal of Cancer, 2016 The stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP3Rs) play pivotal roles in the modulation of Ca2+-regulated pathways from gene transcription to cell apoptosis ...
Jing Wen +4 more
doaj +1 more source
Serum checkpoint molecules in patients with IgG4-related disease (IgG4-RD)
Arthritis Research & Therapy, 2021 Background Immunoglobulin G4-related disease (IgG4-RD) is characterized by increased serum IgG4 concentration and infiltration of IgG4+ plasma cells in the affected organs.
Haruki Matsumoto +14 more
doaj +1 more source
, 2018 Perguruan Tinggi merupakan tingkat pendidikan yang mendekati dunia kerja. Persaingan pada dunia pendidikan yang semakin kompetitif mengharus setiap lembaga pendidikan harus mampu bersaing dengan menciptakan inovasi-inovasi baru yang dapat manarik minat ...
STIM Sukma
core +1 more source
Advanced Science, EarlyView.Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang +10 more
wiley +1 more source
STIM-ulation for the big trial
Swiss Medical Weekly, 2012 Ischaemic heart disease is one of the leading causes of morbidity and mortality in the industrialised world. Although pharmacological and interventional strategies for revascularisation have improved the outcome of ischaemic heart disease, the possibility of reversing progressive ventricular remodeling remains a major unresolved clinical problem ...
openaire +3 more sources
Advanced Electronic Materials, EarlyView.In this study, we developed a cost‐efficient neural probe by replacing traditional gold with an aluminum‐based Ti/Al/Ni multilayer stack. Optimizing this metal architecture suppressed oxidation and ensured robust electrical stability, achieving signal quality comparable to standard gold probes. It enables a highly accessible and economical solution for
Sehwan Park +6 more
wiley +1 more source
STIM and Orai in hemostasis and thrombosis
Frontiers in Bioscience, 2011 At sites of vascular injury, platelets rapidly adhere to the exposed subendothelial extracellular matrix, become activated and, together with the coagulation system, form a plug that seals the lesion. This process is essential to prevent blood loss, however, under pathological conditions it may lead to vessel occlusion.
Attila, Braun +3 more
openaire +2 more sources
Multi-mode imaging of STIM/Orai relocalization.
, 2015 Images in each panel show EGFP-tagged Orai visualized by shadowless TIRF excitation at 488 nm (top left); mCherry-tagged STIM visualized by TIRF excitation at 532 nm (top right); mCherry-tagged STIM visualized by skimming- plane (SP) excitation at 532 nm
Ian Parker (101) +2 more
core +1 more source
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Arthritis &Rheumatology, EarlyView.Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source