Results 201 to 210 of about 61,886,207 (255)

Cytokine‐Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies—A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4⁺ T-cells. [PDF]

Front Immunol
Moreira Gabriel E, Moreaux J, Kaofai C, Majidi Ivari K, Schmouth JF, Goulet JP, Dias J, Wiche Salinas TR, Raymond Marchand L, Khalfi S, Routy JP, Durand M, El-Far M, Tremblay CL, Ancuta P.   +14 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, Volume 3, Issue 3, September 2026.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

TRIM56 Promotes Antiviral Responses Downstream of TLR4. [PDF]

Viruses
Tong X, Li NL, Yang D, Liu BM, Li ZA, Li K.   +5 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Faf2 is required for neural differentiation in embryonic neural progenitor cells. [PDF]

Front Cell Dev Biol
Kakebeen AD, Dunphy L, Hazen HK, Niswander LA.   +3 more
europepmc   +1 more source

All‐Trans Retinoic Acid Promotes Endometrial Regeneration and Angiogenesis Associated With Wnt/β‐Catenin Signaling in a Mouse Model of Intrauterine Adhesion

iNew Medicine, Volume 2, Issue 3, September 2026.
ATRA promotes endometrial regeneration, angiogenesis, and uterine receptivity in intrauterine adhesion, at least in part through activation of Wnt/β‐catenin signaling. ABSTRACT Objective To investigate the therapeutic effects of all‐trans retinoic acid (ATRA) on endometrial repair and the underlying mechanisms.
Ting Luo, Ting Liao, Yunxia Cao, Zhaolian Wei   +3 more
wiley   +1 more source

From RCT to mechanistic study: ATRA reverses myofibroblast activation by reprogramming glucose metabolism via HIC1 and PCK1/2 to attenuate hypertrophic scar formation. [PDF]

Mil Med Res
Li ZC, Zhu YF, Song YJ, Tan ZJ, Liu B, Jiang Y, Xiao HA, Zu DM, Wang T, Shi Y, Jiao Y, Li XY, Xu XB, Shang L, Yu Z, Song BQ.   +15 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury. [PDF]

Cell Prolif
Liu Q, Zhang Z, Hao W, Zhou C, Yang D.
europepmc   +1 more source