Results 11 to 20 of about 233,089 (385)
The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
Nature, 2022 COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung pathology and extrapulmonary complications 1 , 2 . Type I interferons (IFNs) have an essential role in the pathogenesis of COVID-19 (refs 3 – 5 ).
J. Di Domizio +16 more
semanticscholar +1 more source
The Eurozone Crisis: A Constitutional Analysis
Utrecht Journal of International and European Law, 2015 “Every power comes through crisis” has long been a motif of European integration. The financial and sovereign debt crises, which have shaken the European Union (EU) in recent years, are at first glance no different. Treaty reforms,
Anna Sting
doaj +3 more sources
Mitochondrial DNA. Part B. Resources, 2022 Vespa magnifica (Smith) is an aggressive social wasp species of Vespidae family. This species is of medical importance for its dangerous sting, traditional medicinal use and valuable venom components. Here, a complete mitogenome of V.
Xi Feng, Binqiang Xu, Yan Huang
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Nature Communications, 2023 DNA derived from chemotherapeutics-killed tumor cells is one of the most important damage-associated molecular patterns that can activate the cGAS-STING (cyclic GMP-AMP synthase—stimulator of interferon genes) pathway in antigen-presenting cells (APCs ...
Chaoyu Wang +10 more
semanticscholar +1 more source
Business: Theory and Practice, 2016 Corporate social responsibility is considered as an important part of entrepreneur’s strategic behaviour. Its purpose is not only to achieve and maintain the good economic results, but at the same time also effort to do well to the environmental and ...
Monika Hodinková, Zdeněk Sadovský
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Vzpostavitev socialnega svetovalnega dela v avstrijskih solah - od projekta do redne ponudbe [PDF]
, 2013 The contribution introduces the present situation and the basic challenges of school social work in Austria. Starting with the perception of a developing “knowledge society” (Höhne, 2004), school is seen as a life place at which social subjects and ...
Heimgartner, Arno, Sting, Stephan
core +1 more source
Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity
Nature Communications, 2023 The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically hot TME, however, systemic delivery might ...
Xiaona Chen +5 more
semanticscholar +1 more source
Sting jets in simulations of a real cyclone by two mesoscale models [PDF]
, 2010 The existence of sting jets as a potential source of damaging surface winds during the passage of extratropical cyclones has recently been recognized However, there are still very few published studies on the subject Furthermore, although ills known that
Gray, Suzanne Louise +2 more
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Nature Communications, 2023 Lack of sufficient cytotoxic T lymphocytes (CD8+ T cells) infiltration and dysfunctional state of CD8+ T cells are considered enormous obstacles to antitumor immunity. Herein, we construct a synergistic nanoplatform to promote CD8+ T cell infiltration in
Ying Huang +5 more
semanticscholar +1 more source
Gut Microbes, 2021 Although cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling has been well recognized in defending DNA viruses, the role of cGAS-STING signaling in regulating infection of RNA viruses remains largely elusive.
Peifa Yu +5 more
doaj +1 more source