Results 41 to 50 of about 62,318 (309)
Frontiers in Immunology, 2022 NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells.
Deyi Sun +13 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
A technique for reducing supersonic transient loads on internal wind tunnel balances [PDF]
TehnikaDesign of slender supersonic missiles requires a comprehensive experimental support in the form of wind tunnel data for a wide range of flight parameters (angle of attack and Mach number). However, in supersonic wind tunnel testing, the problem exists of
Vuković Đorđe S. +1 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
How to Manage Lionfish Envenomation?
International Journal of Environment and Geoinformatics, 2021 Lionfish have highly toxic venom and envenomation may result in a wide spectrum of complaints in humans ranging from sharp pain to infection and necrosis of the soft tissue.
Selin Gamze SÜMEN, Bayram ÖZTÜRK
doaj +1 more source
ASSIST: Refinement of a Benefits Navigator Intervention Among Low‐Income Pediatric Oncology Families
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Children with cancer living in poverty experience worse survival and quality of life. Interventions connecting low‐income families to benefits (e.g., Supplemental Nutrition Assistance Program [SNAP] improve health outcomes; yet nearly 50% of SNAP‐eligible pediatric oncology families are unenrolled.
Puja J. Umaretiya +11 more
wiley +1 more source
Method for static divergence analysis of sting-mounted wind tunnel models [PDF]
, 2005 Occurrence of static divergence will result in a catastrophic failure of wind tunnel models supported13; on sting or other types of support . The report presents an analysis method that can be used to design and/or13; verify the design of a model-balance-
Sundaramurthy, H
core
STING-Targeted PET Imaging for Specific Detection and Therapeutic Monitoring of Myocarditis [PDF]
Imaging strategies for the specific detection and therapeutic monitoring of myocarditis are still lacking. Stimulator of interferon genes (STING) is a signal transduction molecule involved in an innate immune response.
Bin Zhou (84959) +7 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
MMAE specifically enhanced the cGAMP-STING-mediated NF-kB immune response. [PDF]
(A) A diagram of MMAE promoting STING-mediated NF-kB signaling. (B-E) THP1-Lucia NF-kB (WT, p50 KO and p65 KO) and THP1-Lucia ISG (WT and p65 KO) were treated with cGAMP (0.5 μM) and/or indicated doses of MMAE for 24 h.
Juanjuan Du (1729927) +5 more
core +1 more source