Results 221 to 230 of about 205,346 (308)

ENPP3 drives ccRCC progression by cGAMP hydrolysis and STING-IFN suppression. [PDF]

Cancer Biol Ther
Ma J, Wu Y, Lin G, Sun X, Geng H, Zhang T, Yu D.   +6 more
europepmc   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

An atlas of cGAS-STING signaling in pathophysiological angiogenesis and retinal vascular homeostasis across species. [PDF]

Mol Ther Nucleic Acids
He X, Zeng R, Wen S, Wen Z, Li H, Ai H, Gao R, Fan L, Zhou L, Shi G, Chen Y, Li S.   +11 more
europepmc   +1 more source

Liquid Metal‐Based Stretchable Strain Sensor for Fruit Growth Monitoring

Advanced Materials Technologies, EarlyView.
Schematic overview of the fruit growth sensor development workflow, including sensor fabrication by injection molding, electromechanical and environmental characterization, mechanical stability testing, electronic readout integration, and outdoor field validation for monitoring of fruit growth under practical orchard conditions.
Asad Ullah, Lennert Purnal, Maximilian Krack, Sander Vijgen, Thijs Vandenryt, Dieter Reenaers, Ronald Thoelen, Wim Deferme   +7 more
wiley   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Induction of DNA-mediated immune responses by bacterial extracellular vesicles results in control of murine norovirus infection. [PDF]

Gut Microbes
Zhao G, Mosby-Tourtellot CA, Rosero J, Schultz AC, Khan E, Elamrani O, Ferraro MJ, Kima PE, Jones MK.   +8 more
europepmc   +1 more source

Hierarchical Multi‐Material Architectures With Gradient Design for Dynamic‐Range Flexible Tactile Sensing

Advanced Materials Technologies, EarlyView.
Hierarchical multi‐material TPMS lattices are engineered as flexible tactile sensors by combining soft and stiff elastomeric layers with a conformal conductive coating. The bilayer architecture delivers sensitivity at low pressures while maintaining a broad detectable range under large loads, enabling reliable pressure and vibration monitoring for ...
Reza Noroozi, Domenic Quiquero, Yan Yan Shery Huang, HaoTian Harvey Shi   +3 more
wiley   +1 more source

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis. [PDF]

Sci Adv
Beernaert B, Jady-Clark RL, Shah P, Ramon-Gil E, Lawson NM, Brodtman ZD, Tagore S, Stihler F, Carter AS, Clarke S, Liu T, Zhu WM, Martin JE, Erdal E, Easton A, Campo L, Browne M, Ash S, Raja RQ, Waddell N, Crosby T, Lord SR, Mann DA, Melero I, de Andrea CE, Tijhuis AE, Foijer F, Hammond EM, Akdemir KC, Leslie J, Izar B, Parkes EE.   +31 more
europepmc   +1 more source

Quantum Electrometry of Non‐Volatile Space Charges in Diamond

Advanced Optical Materials, EarlyView.
Charges are generated when nitrogen vacancy qubits in diamond are illuminated by light. Transport and trapping in an electric field leads to the formation of large, stable space charge patterns that dynamically screen applied electric fields, impacting electric field sensing and photoelectric detection.
Russell M Goldblatt, Nikolai Dontschuk, Daniel J McCloskey, Andy M Martin, Alexander A. Wood   +4 more
wiley   +1 more source

Spreading depolarization activates the cGAS-STING pathway and drives cranial nociception: therapeutic potential of STING modulation. [PDF]

J Headache Pain
Soylu KO, Donmez-Demir B, Kilic HB, Sever-Bahcekapili M, Cakir-Aktas C, Kocaefe YC, Karatas H, Yemisci M.   +7 more
europepmc   +1 more source