Results 21 to 30 of about 233,089 (385)
Clinical effectiveness of hymenoptera venom immunotherapy [PDF]
, 2013 Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Aberer, Werner +21 more
core +1 more source
STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. [PDF]
, 2013 UnlabelledSTING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent
Barker, Jeffrey R +6 more
core +2 more sources
Selective STING stimulation in dendritic cells primes antitumor T cell responses
Science immunology, 2023 T cells that recognize tumor antigens are crucial for mounting antitumor immune responses. Induction of antitumor T cells in immunogenic tumors depends on STING, the intracellular innate immune receptor for cyclic guanosine monophosphate–adenosine ...
Bakhos Jneid +19 more
semanticscholar +1 more source
Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]
, 2008 We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla +9 more
core +1 more source
Critical Role of the cGAS-STING Pathway in Doxorubicin-Induced Cardiotoxicity
Circulation Research, 2023 Background: Doxorubicin is an effective chemotherapy drug for treating various types of cancer. However, lethal cardiotoxicity severely limits its clinical use.
Weihua Luo +22 more
semanticscholar +1 more source
DEVELOPMENTS WITHIN SOCIAL PEDAGOGY IN AUSTRIA: PERSPECTIVES FOR WORK WITH CHILDREN AND YOUNG PEOPLE
International Journal of Child, Youth & Family Studies, 2018 This article traces the history of social pedagogy in Austria, which shows some differences from the German history of social pedagogy. In the 1920s and the first half of the 1930s, the development of social pedagogy led to interesting approaches in the ...
Stephan Sting
doaj +1 more source
eHealth International, 2002 I am an optimist, but can't help noticing that disappointment follows every great invention. For a while. As athletes say, "no pain, no gain". The eHealth highway has its own detours and potholes, but we are compelled by circumstances and opportunities to travel upon it. We humans are gullible innocents.
openaire +3 more sources
Frontiers in Immunology, 2022 NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells.
Deyi Sun +13 more
doaj +1 more source
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
Nature Communications, 2023 STING is an intracellular sensor of pathogen- or host-derived DNA. In this study, the authors identify an ESCRT complex that regulates STING degradation, thus acting as a homeostatic regulator of STING signalling and type-I interferon responses ...
M. Gentili +11 more
semanticscholar +1 more source