Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]
, 2008 We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
Rueff, F. +4 more
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Manganese facilitated cGAS-STING-IFNI pathway activation induced by ionizing radiation in glioma cells [PDF]
, 2023 After irradiation, double-stranded DNA leaked into the cytoplasm activates the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, leading to the production of type I interferon (IFNI).
Ying Yang (24175) +8 more
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Mitochondrial DNA. Part B. Resources, 2022 Vespa magnifica (Smith) is an aggressive social wasp species of Vespidae family. This species is of medical importance for its dangerous sting, traditional medicinal use and valuable venom components. Here, a complete mitogenome of V.
Xi Feng, Binqiang Xu, Yan Huang
doaj +1 more source
Table1_Development of a risk model to predict prognosis in breast cancer based on cGAS-STING-related genes.docx [PDF]
, 2023 Background: Breast cancer (BRCA) is regarded as a lethal and aggressive cancer with increasing morbidity and mortality worldwide. cGAS-STING signaling regulates the crosstalk between tumor cells and immune cells in the tumor microenvironment (TME ...
Zhihui Feng (748181) +4 more
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The Eurozone Crisis: A Constitutional Analysis
Utrecht Journal of International and European Law, 2015 “Every power comes through crisis” has long been a motif of European integration. The financial and sovereign debt crises, which have shaken the European Union (EU) in recent years, are at first glance no different. Treaty reforms,
Anna Sting
doaj +3 more sources
Image_1_Extracellular vesicles from A23187-treated neutrophils cause cGAS-STING-dependent IL-6 production by macrophages.tif [PDF]
, 2022 In response to several types of bacteria, as well as pharmacological agents, neutrophils produce extracellular vesicles (EVs) and release DNA in the form of neutrophil extracellular traps (NETs).
Ellen M. Palmatier (13172649) +4 more
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All-Atom Simulations Uncover Structural and Dynamical Properties of STING Proteins in the Membrane System [PDF]
, 2022 Recent studies have shown that the stimulator of interferon gene (STING) protein plays a central role in the immune system by facilitating the production of Type I interferons in cells.
Rachel, Payne +2 more
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A proposed model for the regulation of NLRP3 inflammasome activation mediated by the cGAS-STING-NLRP3 pathway. [PDF]
, 2020 Left: In the mock infection, all these proteins are in the cytoplasm. NLRP3 contains an N-terminal pyrin domain (PYD), a NACHT-associated domain (NAD) and 7 C-terminal leucine rich repeats (LRR). ASC (the apoptosis-associated speck-like protein with CARD
Weijie Chen (1321836) +16 more
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Specific association of TBK1 with the trans-Golgi network following STING stimulation
Cell Structure and Function, 2022 Stimulator of interferon genes (STING) is essential for the type I interferon response induced by microbial DNA or self-DNA leaked from mitochondria/nuclei.
Haruka Kemmoku +3 more
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Toxins, 2021 The jellyfish species that inhabit the Mediterranean coastal waters are not lethal, but their stings can cause severe pain and systemic effects that pose a health risk to humans. Despite the frequent occurrence of jellyfish stings, currently no consensus
Ainara Ballesteros +5 more
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