Results 61 to 70 of about 409,058 (151)

MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer

Scientific Reports
Glycosylation changes of circulating proteins carrying the CA19-9 antigen may offer new targets for detection methods to be explored for the diagnosis of epithelial ovarian cancer (EOC). Search for assay designs for targets initially captured by a CA19-9
Shamima Afrin Ruma, Rufus Vinod, Shruti Jain, Kaisa Huhtinen, Johanna Hynninen, Janne Leivo, Kim Pettersson, Karin Sundfeldt, Kamlesh Gidwani   +8 more
doaj   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Hominoid‐specific calretinin‐immunopositivity of the optic radiation (geniculocalcarine tract)

The Anatomical Record, Volume 309, Issue 5, Page 1343-1367, May 2026.
Calretinin‐immunostained coronal section through the primary (V1) and extrastriate (ExSt) cortex of the lar gibbon. Note that the optic radiation (OR) is strongly calretinin‐immunoreactive. This calretinin‐immunopositivity of the OR distinguishes the Hominoidea from other primates in terms of the neurochemistry of the OR.
Nelyane N. M. Santana, Jordan Swiegers, Mads F. Bertelsen, Chet C. Sherwood, José R. L. P. Cavalcanti, Paul R. Manger   +5 more
wiley   +1 more source

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

ChemistryEurope, Volume 4, Issue 5, May 2026.
An engineered macrophage galactose‐type lectin (MGL)‐based conjugate (mMGL‐vcMMAE), incorporating an exposed cysteine for site‐specific drug linkage, preserves stability, binding profile, and affinity of the native MGL carbohydrate recognition domain. It also selectively targets Tn/STn‐expressing cancer cells and shows recognition of colorectal cancer ...
Carlos D. L. Lima, Rafaela Abrantes, Victor Lorrain, Joana Gomes, Reyes Núñez‐Franco, João P. M. António, Catarina Gomes, Ana Gimeno, Benedita A. Pinheiro, Angelina S. Palma, Jesús Jiménez‐Barbero, Pedro M. P. Gois, Gonzalo Jiménez‐Osés, Sandra J. van Vliet, Celso A. Reis, Filipa Marcelo   +15 more
wiley   +1 more source

STN-projecting ACC neurons regulate pain thresholds, place preference, and depression-like behavior.

(A) Schematic diagram of virus injections and optical fiber implantation for optogenetic activation of STN-projecting ACC neurons. (B and C) Representative images of retrograde transfection of STN-projecting ACC neurons with ChR2.
Jun-Li Cao (312500), Cheng Xiao (585188), Yuan Gao (159945), Shu-Ting Bao (18010650), Chunyi Zhou (4965526), Cui Yin (8578461), Ying-Di Wang (18010647), Jin Chen (130241), Tao Jia (756099)   +8 more
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Synthesis and immunological evaluation of MUC1 glycopeptide conjugates bearing N-acetyl modified STn derivatives as anticancer vaccines

, 2016
Glycoprotein MUC1 is an attractive target for anti-tumor vaccine development. However, the weak immunogenicity of MUC1 remains a significant problem.
Huo, Chang-Xin, Ye, Xin-Shan, Song, Chengcheng, Zheng, Xiu-Jing, Xiao, An, Gui, Yue   +5 more
core   +1 more source

Stellsysteme in heisser Struktur Abschlussbericht

, 1993
This report describes the investigations handled by STN within the E09 Project in accordance with the working plan item ''7.3 Analytical Investigations''.
Saenger, U., STN Systemtechnik Nord GmbH, Bremen (Germany)   +1 more
core  

Enterobacterial common antigen in mutant strains of Salmonella. [PDF]

, 1978
A good correlation was found to exist between the serologically determined presence of enterobacterial common antigen (ECA) and the amount of the rare sugar constituent D-mannosaminuronic acid.
Mayer, H., Männel, Daniela N., Mäkelä, P. H.   +2 more
core   +1 more source

Synthetic and Immunological Studies of sTn Derivatives Carrying Substituted Phenylacetylsialic Acids as Cancer Vaccine Candidate

, 2016
To search for effective cancer vaccines based on sTn, a sialylated tumor-associated carbohydrate antigen (sialo-TACA) expressed by a number of tumors, four unnatural N-acyl sTn derivatives, including 5′-N-p-methylphenylacetyl sTn (sTnNMePhAc), 5′-N-p ...
Zhongwu Guo (673969), Qianli Wang (2121643)   +1 more
core   +1 more source