Results 21 to 30 of about 53,222 (261)
The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C. elegans. [PDF]
PLoS Genetics, 2012 The Caenorhabditis elegans left and right AWC olfactory neurons communicate to establish stochastic asymmetric identities, AWC(ON) and AWC(OFF), by inhibiting a calcium-mediated signaling pathway in the future AWC(ON) cell. NSY-4/claudin-like protein and
Yi-Wen Hsieh +2 more
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Signaling pathways have an inherent need for noise to acquire information
BMC Bioinformatics, 2020 Background All living systems acquire information about their environment. At the cellular level, they do so through signaling pathways. Such pathways rely on reversible binding interactions between molecules that detect and transmit the presence of an ...
Eugenio Azpeitia +2 more
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On the origin and characteristics of noise-induced Lévy walks of E. coli. [PDF]
PLoS ONE, 2011 Lévy walks as a random search strategy have recently attracted a lot of attention, and have been described in many animal species. However, very little is known about one of the most important issues, namely how Lévy walks are generated by biological ...
Franziska Matthäus +3 more
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Elucidating the sources of β-catenin dynamics in human neural progenitor cells. [PDF]
PLoS ONE, 2012 Human neural progenitor cells (hNPCs) form a new prospect for replacement therapies in the context of neurodegenerative diseases. The Wnt/β-catenin signaling pathway is known to be involved in the differentiation process of hNPCs. RVM cells form a common
Orianne Mazemondet +4 more
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eLife, 2017 We present in vivo single-cell FRET measurements in the Escherichia coli chemotaxis system that reveal pervasive signaling variability, both across cells in isogenic populations and within individual cells over time.
Johannes M Keegstra +5 more
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Stochastic model for detection of signals in noise [PDF]
Journal of the Optical Society of America A, 2009 Fifty years ago Birdsall, Tanner, and colleagues made rapid progress in developing signal detection theory into a powerful psychophysical tool. One of their major insights was the utility of adding external noise to the signals of interest. These methods have been enhanced in recent years by the addition of multipass and classification-image methods ...
Stanley A, Klein, Dennis M, Levi
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Analysis of stochastic Petri nets with signals [PDF]
Performance Evaluation, 2012 Product-form models facilitate the efficient analysis of large stochastic models and have been sought after for some three decades. Apart from the dominating work on queueing networks, some product-forms were found for stochastic Petri nets (SPNs) that allow fork-join constructs and for queueing networks extended to include special customers called ...
MARIN, Andrea +2 more
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Multiple signaling pathways coordinate to induce a threshold response in a chordate embryo. [PDF]
PLoS Genetics, 2013 In animal development, secreted signaling molecules evoke all-or-none threshold responses of target gene transcription to specify cell fates. In the chordate Ciona intestinalis, the neural markers Otx and Nodal are induced at early embryonic stages by ...
Naoyuki Ohta, Yutaka Satou
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Patterning the insect eye: From stochastic to deterministic mechanisms.
PLoS Computational Biology, 2018 While most processes in biology are highly deterministic, stochastic mechanisms are sometimes used to increase cellular diversity. In human and Drosophila eyes, photoreceptors sensitive to different wavelengths of light are distributed in stochastic ...
Haleh Ebadi +6 more
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Computational Modeling for the Activation Cycle of G-proteins by G-protein-coupled Receptors [PDF]
Electronic Proceedings in Theoretical Computer Science, 2010 In this paper, we survey five different computational modeling methods. For comparison, we use the activation cycle of G-proteins that regulate cellular signaling events downstream of G-protein-coupled receptors (GPCRs) as a driving example.
Yifei Bao +3 more
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