Results 91 to 100 of about 1,092,982 (283)
Genome Sequences of Three Lactobacillus Species Strains of the Stomach of the White-Footed Deermouse (Peromyscus leucopus). [PDF]
, 2019 Three colony types of Lactobacillus were isolated from the stomach of LL colony stock Peromyscus leucopus deermice, a reservoir for several human zoonoses.
Barbour, Alan G +2 more
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Plasticity of differentiated cells in wound repair and tumorigenesis, Part II: Skin and intestine [PDF]
, 2018 Recent studies have identified and begun to characterize the roles of regenerative cellular plasticity in many organs. In Part I of our two-part Review, we discussed how cells reprogram following injury to the stomach and pancreas.
Burclaff, Joseph, Mills, Jason C
core +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Stereotactic Magnetic Resonance-guided Online Adaptive Radiotherapy for Oligometastatic Breast Cancer: A Case Report. [PDF]
, 2018 We present a case of durable local control achieved in a patient treated with stereotactic magnetic resonance-guided adaptive radiation therapy (SMART) for an abdominal lymph node in the setting of oligometastatic breast cancer.
Cao, Minsong +7 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Stomach cancer incidence in Southern Portugal 1998-2006:a spatio-temporal analysis [PDF]
, 2012 Understanding geographical differences in health, particularly in small areas, became a major concern of epidemiologists. Geographical association studies and, more recently, several spatial disease mapping studies have emerged due to the development of
Amaral Turkman, Antónia +5 more
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陆军军医大学学报Objective To investigate the association between Framingham steatosis index (FSI) and the risk of gallstone disease in order to evaluate its potential as a risk marker and simple screening tool. Methods A cross-sectional study was conducted on 5 705
ZHANG Qizhen, LIU Sutong
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Effects of ingestion of cold and hot water on the course of thermal changes in the stomach and intestine [PDF]
With the use of a thermocouple and mirror galvanometer, calibrated before the experiment and after each test, it was found that the normal temperature in the esophagus is 0.1-0.4 C higher than in the oral cavity, the temperature in the duodenum is ...
Batinkov, Y. L.
core +1 more source