Results 191 to 200 of about 159,363 (373)
A New Serologic Test for the Detection of Viral Antigens: Its Application to the Viruses of Hog Cholera and Vesicular Stomatitis, [PDF]
Daniel Segrè
openalex +1 more source
Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
wiley +1 more source
PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou +17 more
wiley +1 more source
Selection of Host Plasma Membrane Lipids by HIV‐1 Gag Protein
Enrichment of sphingomyelin in the HIV‐1 envelope arises from Gag binding to PI(4,5)P2, which triggers reorganization of plasma membrane sphingomyelin/cholesterol domains through unknown mechanisms. We propose that cholesterol‐mediated interleaflet coupling between sphingomyelin and PI(4,5)P2, rather than interdigitation, underlies Gag‐induced lipid ...
Nario Tomishige +2 more
wiley +1 more source
Lipid Composition of Purified Vesicular Stomatitis Viruses [PDF]
James J. McSharry, Robert R. Wagner
openalex +1 more source
Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas
Structure of the "hit‐compound" found and the proposed interaction with the active site of the TMPRSS2 protease, involving a reversible mechanism of action, are shown. The COVID‐19 pandemic highlighted the urgent need for effective antiviral treatments targeting SARS‐CoV‐2.
Marco Minneci +6 more
wiley +1 more source
Editorial: Methods in experimental pharmacology 2023
Somasundaram Arumugam +2 more
doaj +1 more source
Effects of glycyrrhizin on healing and prevention of recurrent aphthous stomatitis in hamster models. [PDF]
Shiba F +6 more
europepmc +1 more source

