Results 101 to 110 of about 638,467 (318)

Physiological and biochemical changes in imported litchi fruit [PDF]

open access: yes, 2010
It is important to determine the appropriate conditions for maintaining postharvest quality of litchi fruit after arrival from overseas markets. The present study, therefore, aimed to detail the effects of different storage conditions on physiological ...
Somboonkaew, Nettra
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Evaluation and Optimization of Quality Based on the Physicochemical Characteristics and Metabolites Changes of Qingpi during Storage

open access: yes, 2023
Qingpi, the dried immature pericarp of Citrus reticulata Blanco, is a commonly used medicinal food with some health-promoting benefits. In general, it is essential that Qingpi be stored for a period of time, but there are no reports about the number of ...
Cui Wu   +5 more
core   +1 more source

Effects of Coriolus versicolor-fermented sweet potato pulp water on yogurt: bioactive components, functional properties, and in vitro gut microbiota modulation

open access: yesFood Chemistry: X
In the sweet potato starch processing industry, large volumes of organic wastewater are generated, yet their utilization remains limited. This study introduces a novel strategy for yogurt enhancement by incorporating Coriolus versicolor-fermented sweet ...
Qin Cen   +8 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

On-Tree Fruit Bagging and Cold Storage Maintain the Postharvest Quality of Mango Fruit

open access: yes, 2022
The present study investigates the influence of on-tree fruit bagging on the quality and shelf life of mango (Mangifera indica L. cv. ‘Samar Bahisht Chaunsa’) during cold storage (12 °C ± 1; 85–90% RH) for 0, 10 and 20 days ...
Sami Ullah   +13 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

OPTIMIZATION FOR FRUIT QUALITY DURING A STORAGE PROCESS

open access: yesIFAC Proceedings Volumes, 1995
Abstract Plant control systems are characterized by complexity and uncertainty. This paper studies the application of an intelligent control technique, including neural networks and genetic algorithms, to the optimization of fruit storage process. Two optimization problems were considered.
T. Morimoto   +3 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Effect of bird age and storage system on physical properties of eggs from brown laying hens

open access: yes, 2010
A total of 108 eggs from a group of 100 brown laying hens housed in standard cages were analyzed. Thirty-six eggs were retired when the hens had 30 week of age, other 36 eggs were retired when the hens had 35 week of age and the remaining 36 eggs were ...
Daza Andrada, Argimiro   +4 more
core  

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