Results 111 to 120 of about 8,431,632 (292)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Introduction to industrial carbon capture and storage

, 2016
Carbon capture and storage, or CCS, is a process used to capture carbon dioxide gas (CO2) that is produced by power stations or other types of industrial facilities.
Global Carbon Capture and Storage Institute
core  

Structural Characterization, Phenolic Acid Modification, and Antioxidant Activities of Polysaccharide From Mogroside Waste Liquid of Siraitia grosvenorii

Food Frontiers
To improve the comprehensive utilization of Siraitia grosvenorii (Swingle) C. Jeffrey, a novel polysaccharide (SGP) was isolated from the mogroside waste liquid of S. grosvenorii.
Jiajing Duan, Yufeng Sun, Bo Wang, Qinfei Xie, Yang Ju, Fengzhong Wang, Bei Fan   +6 more
doaj   +1 more source

Growth and Genome Features of Non-O1/O139 Vibrio cholerae Isolated from Three Species of Common Freshwater Fish

Diversity
Vibrio cholerae is the etiological agent of cholera in humans. The bacterium is frequently detected in aquatic products worldwide. However, the current literature on the genome evolution of V. cholerae of aquatic animal origins is limited.
Xinchi Qin, Lianzhi Yang, Yingwei Xu, Lu Xie, Yongjie Wang, Lanming Chen   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Modeling of Hydro-Pneumatic Energy Storage Using Pump Turbines [PDF]

, 2011
Modelling of a hydro-pneumatic energy storage system is presented in this paper. Hydro pneumatic storage aims to combine the good efficiency of hydraulic energy conversion and the space flexibility of pneumatic storage.
COLAS, Frédéric, DAZIN, Antoine, ORTEGO, Egoï, CAIGNAERT, Guy, COUTIER-DELGOSHA, Olivier   +4 more
core  

Analysis of the Differences in Composition and Quality of Geographical Indication Mutton from Two Regions in Xinjiang

Shipin gongye ke-ji
To clarify the quality characteristics of sheep breeds in different regions of Xinjiang, taking Kazakh sheep from Northern and Lop sheep from Southern Xinjiang, after slaughter, the longest muscles of the back were selected and their edible quality ...
Zixin ZHENG, Minghui GU, Dequan ZHANG, Cheng LI, Wujun LIU, Xiaochun ZHENG   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Environmental Compatibility and Genome Flexibility of Klebsiella oxytoca Isolated from Eight Species of Aquatic Animals

Diversity
Klebsiella oxytoca is an emerging pathogen that can cause life-threatening infectious diseases in humans. Recently, we firstly reported for the first time the presence of K. oxytoca in edible aquatic animals.
Shuo Sun, Tingting Gu, Yafei Ou, Yongjie Wang, Lu Xie, Lanming Chen   +5 more
doaj   +1 more source