This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Factors affecting the success of store brands in Turkish retailing market [PDF]
Tulin Ural
doaj
Prioritizing psychological factors in young consumers' coffee brand preferences through a novel behavioral leadership fuzzy decision-making modelling. [PDF]
Eti S +4 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The effect of removing point-of-purchase price discounts on college students' future tobacco use susceptibility depends on price sensitivity. [PDF]
Martino SC +5 more
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Accelerating tobacco regulatory science in the United States: The center for rapid surveillance of tobacco. [PDF]
Delnevo CD +5 more
europepmc +1 more source
The increasing power of store brands: Building loyalty and market share. [PDF]
Steenkamp, J., Dekimpe, M.G.
core
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Automated Detection of Digital Alcohol Marketing Using SCANNER: An Integrated Deep-Learning Approach. [PDF]
Martino F +4 more
europepmc +1 more source

