Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Information acquisition and cognitive processes during strategic decision-making: Combining a policy-capturing study with eye-tracking data. [PDF]
PLoS One, 2022 Pizzo A +3 more
europepmc +1 more source
Mental Frames and Organizational Decision-making: Facing the Challenges of Change [PDF]
Adjusting to the strategic, business and economic changes requires efficient decision-making procedures which can in turn be highly affected by the underlying mental frames that the leaders of the organization hold.
Fulton, Murray E., Lamprinakis, Lampros
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Leveraging Data Analytics for Strategic Logistics Decision-Making
International Journal of Applied Research in Business and ManagementThe evolving landscape of global commerce has transformed logistics from a tactical function into a critical strategic lever. As supply chains grow increasingly complex and demand more responsiveness, organizations are turning to data analytics to ...
Pamela Zama Nomzaza
doaj +1 more source
IT-business alignment, big data analytics capability, and strategic decision-making: Moderating roles of event criticality and disruption of COVID-19. [PDF]
Decis Support Syst, 2022 Chen L, Liu H, Zhou Z, Chen M, Chen Y.
europepmc +1 more source
Strategic decision making frameworks
Policy Quarterly, 2010 The New Zealand Council for Infrastructure Development (NZCID) considers that there is a need for a much more strategic, more sophisticated and better balanced approach to prioritisation of infrastructure investment in New Zealand. This was one of the key reasons why NZCID was a cornerstone funder of the New Zealand Centre for Advanced Engineering ...
openaire +2 more sources
Balancing operating revenues and occupied refurbishment costs 1: problems of defining project success factors and selecting site planning methods [PDF]
, 2007 In planning the refurbishment of railway stations the spatial needs of the contractor and of the ongoing business stakeholders have to be balanced. A particular concern is the disruptive effect of construction works upon pedestrian movement.
Kelsey, J
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Investment analysis of plum brandy production – methodology approach [PDF]
The major prerequisite of successful entrepreneurship venture is quality of decision-making process. Decision in investment is the most important financial decision.
Hadelan, Lari
core +1 more source