Results 91 to 100 of about 812,510 (332)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Sea Guidelines. A Comparative Analysis: First Outcomes

TeMA: Journal of Land Use, Mobility and Environment, 2014
The European Directive 2001/42/EC (Directive) has introduced the Strategic Environmental Assessment (SEA), a procedure for assessing the effects of certain plans and programs on the environment.
Andrea De Montis, Antonio Ledda, Simone Caschili, Amedeo Ganciu, Mario Barra, Gianluca Cocco, Agnese Marcus   +6 more
doaj   +1 more source

Analysing students' environmental awareness profile using strategic environmental assessment. [PDF]

F1000Res, 2021
Khoiri A, Khoiri A, Sunarno W, Sajidan S, Sukarmin S.   +4 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Sacrificing Wilderness for Renewables? Land Artificialization from Inadequate Spatial Planning of Wind Energy in Evvoia, Greece

Land
The REPowerEU Plan calls for a massive speed-up of renewable energy, which can undermine nature conservation. We explored the impact of an industrial-scale wind power project planned inside a Natura 2000 site (Special Protected Areas for birds) in the ...
Vassiliki Kati, Konstantina Spiliopoulou, Apostolis Stefanidis, Christina Kassara   +3 more
doaj   +1 more source

Planning for the reuse of redundant defence estate: disposal processes, policy frameworks and development impacts [PDF]

, 1998
This paper reviews recent research and other literature concerning the planning and development of redundant defence estate. It concentrates on UK sources but includes reference to material from Europe and the North America were it is relevant for ...
Doak, Joe
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Considering Vermont\u27s Future in a Changing Climate: The First Vermont Climate Assessment [PDF]

, 2014
The Vermont Climate Assessment (VCA) paints a vivid picture of a changing climate in Vermont and calls for immediate strategic planning to sustain the social, economic and environmental fabric of our state.
Baker, Daniel V, Carlson, Sam, Ford, Sarah, Galford, Gillian L, Hoogenboom, Ann, Nash, Julie, Palchak, Elizabeth, Pears, Sarah, Underwood, Kristen   +8 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Sustainability appraisal: Jack of all trades, master of none? [PDF]

, 2009
Sustainable development is a commonly quoted goal for decision making and supports a large number of other discourses. Sustainability appraisal has a stated goal of supporting decision making for sustainable development.
Alan J. Bond, Angus Morrison-Saunders, Ayre G., Bartlett R. V., Bekker M. P M, Bell S., Benson D., Bond A. J., Buckingham S., Cabeza Gutés M., Cherp A., Clark J., Clarke A. H., Dalal-Clayton B., Donnelly A., Donnelly A., Foxon T. J., Galobardes B., Gasparatos A., George C., Grey W., Hajer M. A., Jacob M., Kuhn T., Lawrence D. P., Leknes E., Luke T. W., Martin E. J., Mebratu D., Morrison-Saunders A., Morrison-Saunders A., Nykvist B., O'Riordan T., Owens S., Oxley T., Pope J., Pope J., Raina R. S., Ramos T. B., Redclift M. R., Russel D., Sankey H., Sheate W., Steinemann A., Svarstad H., Theobald W. F., Thérivel R., Thérivel R., Williams C. C., Wood C.   +49 more
core   +2 more sources