Results 91 to 100 of about 239,426 (298)

STRATEGIC ENVIRONMENTAL ASSESSMENT OF THE ADJUSTMENT PROCESS OF THE CITY MASTERPLAN TO THE SARDINIAN REGIONAL LANDSCAPE PLAN: THE CASE OF CITY MASTERPLAN OF ALGHERO, SARDINIA (ITALY) [PDF]

open access: yes, 2011
Strategic Environmental Assessment (SEA) in the context of the enactment of the Directive 2001/42/CE is at the core of the adjustment process of provincial and city Masterplan to the Sardinian Regional Landscape Plan (RLP).
Isola, Federica, Pira, Cheti
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

KAJIAN LINGKUNGAN HIDUP STRATEGIS (KLHS) DALAM MENJAMIN TERPELIHARANYA DAYA DUKUNG DAN DAYA TAMPUNG LINGKUNGAN HIDUP (DDDTLH) BAGI PEMBANGUNAN BERKELANJUTAN [PDF]

open access: yes, 2016
Policy, Plan, andProgram(PPP) of development that less or even do not considerthe environmental interest is upstreamoftheproblemsof environmental andnatural resources degradation.
Satmaidi, Endra
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Module B – Health in strategic environmental assessment (SEA)

open access: yes, 2013
This three day module focuses on the role of strategic environmental assessment in relation to integrating health issues. During the module participants will be introduced to SEA concepts and process dynamics, as well as to health issues when considered from a strategic perspective.
Broeder, Lea den   +3 more
openaire   +2 more sources

Integrating climate change adaptation into municipal masterplans through Strategic Environmental Assessment (SEA)

open access: yesTeMA: Journal of Land Use, Mobility and Environment
Adaptation to climate change and the need to deal with its impacts pose in evidence how important it is to identify and implement new planning practices that integrate these profiles into land-use policy-making.
Federica Isola   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Health and Strategic Environmental Assessment [PDF]

open access: yes, 2013
This paper reflects on how human health is dealt with in strategic environmental assessment (SEA). It is shown that in current practice, whilst aspects affecting physical aspects of health (e.g.
Fischer, Thomas
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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