Results 101 to 110 of about 11,053,990 (295)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Strategic environmental assessment implementation of transport and mobility plans. The case of Italian regions and provinces

Journal of Agricultural Engineering, 2016
Transport and mobility plans imply strategies and actions that affect the environment. The European Union has introduced in 2001 the strategic environmental assessment (SEA) to take into account and mitigate adverse environmental effects in planning and ...
Andrea De Montis, Simone Caschili, Amedeo Ganciu, Antonio Ledda, Filippo Paoli, Federico Puddu, Mario Barra   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Strategic environmental assessment of spatial plans in the light of own research

Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2019
Strategic environmental assessment constitutes the least explored in research kind of an environmental assessment in comparison to environmental impact assessment and habitat assessment.
Jolanta Harasymiuk, Wojciech Drozd
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Strategic environmental assessment and land use planning: An international evaluation

, 2005
Strategic Environmental Assessment and Land Use Planning covers not only how much such SEAs are carried out and in what context, but whether they are effective and why.
Short, Michael
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Strategic environmental assessment procedure with the example of a detailed regulation plan for a business economy complex [PDF]

Arhitektura i Urbanizam, 2006
In the Republic of Serbia Strategic Environmental Assessment Law is establishing methodological and procedural framework which promote the Directive 2001/42/EC of the European Parliament and the Council of 27 June 2002 on the assessment of the effects of
Josimović Boško, Crnčević Tijana
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

GIS-based Strategic Environmental Assessment

The intrinsic spatial nature of environmental assessment and, indeed, most planning decisions can significantly benefit from GIS-based analyses and outcomes.
González Del Campo, Ainhoa, Geneletti, Davide   +1 more
core   +1 more source