Results 81 to 90 of about 11,053,990 (295)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Assessments in Policy-Making: Case Studies from the Arctic Council [PDF]

open access: yes, 2014
Julkaistu versioei tietoa ...
Kankaanpää, Paula   +5 more
core   +2 more sources

Module B – Health in strategic environmental assessment (SEA)

open access: yes, 2013
This three day module focuses on the role of strategic environmental assessment in relation to integrating health issues. During the module participants will be introduced to SEA concepts and process dynamics, as well as to health issues when considered from a strategic perspective.
Broeder, Lea den   +3 more
openaire   +2 more sources

Analysis for biotechnology innovations using Strategic Environmental Assessment (SEA): [PDF]

open access: yes
" Meeting the food needs of the world's growing population while reducing poverty and protecting the environment is a major global challenge. Genetically modified crops appear to provide a promising option to deal with this challenge.
Gaskell, Joanne   +6 more
core  

Environmental Assessment of Proposed Trunk Sewer Lines and Channelization of Singac and Naachtpunkt Brooks, Wayne Township, New Jersey

open access: yes, 1973
This report provides an environmental assessment of the proposed plans to install trunk sewer lines in and channelize the Singac and Naachtpunkt Brooks in Wayne Township.

core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

THE ROLE OF SEA IN INTEGRATING THE ENVIRONMENTAL CONSIDERATIONS INTO THE PLANNING OF HYDROENERGETIC PLANTS [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2013
The present paper offers an analysis of the concept of SEA and its role in the development of hydroenergetic plant planning. The article provides information related to the institutional aspects of the strategic environmental assessment processes, at the
Claudia-Thora Ionescu   +2 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Environmental Assessment Study of the 201 Facilities Plan for Wayne Township, N.J.

open access: yes, 1976
This report presents plans for connecting all of Wayne Township's sewerage systems into one unified system. As Wayne Township was designated a 201 Study Area by the New Jersey Department of Environmental Protection (NJDEP), this report serves as the ...

core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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