EVALUATING STRATEGICAL SPATIAL PLANNING APPROACH IN CASE OF ISTANBUL [PDF]
In Turkey, The law of Institutional Strategic Planning (ISP) issued in order to compliance with European Union is unfortunately insufficient recovering spatial-oriented strategic planning (SSP) decisions.
Rahmi ERDEM, Sinan LEVEND
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Framing access to essential medicines in the context of Universal Health Coverage: a critical analysis of health sector strategic plans from eight countries in the WHO African region. [PDF]
BMC Health Serv Res, 2022 Mhazo AT, Maponga CC.
europepmc +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Strategic objectives and development plans of beginning farmers
Agricultural and Food Science, 2012 Taking over the management and ownership of a farm contributes positively to farm growth but little is known about how farmers succeed after the starting phase.
Leena Rantamäki-Lahtinen +1 more
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Assessing inclusion of trans people in HIV national strategic plans: a review of 60 high HIV prevalence countries. [PDF]
J Int AIDS Soc, 2021 Sherwood J +5 more
europepmc +1 more source
TOURISM DEVELOPMENT PLANNING IN SELECTED EU COUNTRIES [PDF]
Tourism development planning is now part of the regional policies of all Member States of the European Union. Strategic plans at national or regional level are specific instruments of regional management, which contain results of the planning process and
Martin LUŠTICKÝ +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source