Results 141 to 150 of about 1,042,917 (337)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Industrial production and temporary development after the Emilian Earthquake.
The earthquake that on the 20th of May hit Emilia has not been one of the most disastrous in modern Italian history, but it has highlighted the problem of preservation of industrial activities during a reconstruction process.
Matteo Scamporrino
doaj
From Master Plan to Vision Plan: The Changing Role of Plans and Plan making in City development (with reference to Mumbai) [PDF]
Master plans are the traditional instruments used by urban local governments in India as forward planning tools by anticipating urban development and making provisions for the same in terms of (a) the allocation of land for various uses, (b) the ...
Ramakrishna NALLATHIGA
core
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The Role of Knowledge in the prevention of natural hazards and related risks.
Human activities, especially over the last two centuries, have had a huge impact on the environment and the landscape. Mankind is able to control and induce landscape changes but is subject to natural processes and hazards due to severe and extreme ...
Enrico Miccadei, Tommaso Piacentini
doaj
Further Education Funding Council : circular : 98/06 : strategic plans including financial forecasts : 1997-98 to 1999-2000 [PDF]
"Provides information derived from an analysis of strategic planning information provided to the Council by institutions in July 1997" -- front ...
core
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
In Italy, recent University reforms, a research quality assessment exercise, and the selection of academics by means of innovative procedures are all accelerating the discussion on the specificity ofresearch on spatial planning and urban design.
Bruno Zanon
doaj
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

