Results 11 to 20 of about 66,927 (286)

Analytical data of synthesized deuterated isopropyl myristate and data about the influence of IPM/IPMdeut on the thermodynamics and morphology of 2D Stratum Corneum models

open access: yesData in Brief, 2017
The data in this article shows the effect of isopropyl myristate (IPM) on a 2D Stratum Corneum lipid model. In the first part, the analytical characterization of the synthesized deuterated isopropyl myristate is given.
J.S.L. Oliveira   +3 more
doaj   +1 more source

Proderm technology: a water- based lipid delivery system for dermatitis that penetrates viable epidermis and has antibacterial effects. [PDF]

open access: yes, 2019
BackgroundA defective skin barrier and bacterial colonization are two important factors in maintenance and progression of atopic dermatitis and chronic allergic/irritant hand dermatitis.
Caputo-Janhager, Melinda   +4 more
core   +3 more sources

Human epidermal lipids: characterization and modulations during differentiation

open access: yesJournal of Lipid Research, 1983
Using thin-layer chromatography and glass capillary gas-liquid chromatography, we have quantitated the lipids in the germinative, differentiating, and fully cornified layers in human epidermis.
M A Lampe, M L Williams, P M Elias
doaj   +1 more source

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

open access: yes, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela   +5 more
core   +1 more source

Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis

open access: yesJournal of Lipid Research, 2003
To clarify the functional relevance of sphingomyelin (100) deacylase to the ceramide deficiency seen in atopic dermatitis (AD), we developed a new highly sensitive method and measured the metabolic intermediate sphingosylphosphorylcholine (SPC) that ...
Reiko Okamoto   +5 more
doaj   +1 more source

Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]

open access: yes, 2019
© 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria   +5 more
core   +2 more sources

Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency

open access: yesJournal of Lipid Research, 2018
Neu-Laxova syndrome (NLS) is a very rare autosomal recessive congenital disorder characterized by disturbed development of the central nervous system and the skin and caused by mutations in any of the three genes involved in de novo l-serine biosynthesis:
Takuya Takeichi   +14 more
doaj   +1 more source

A Note on the Trandermal Delivery of Clenbuterol [PDF]

open access: yes, 1992
A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core   +1 more source

10-Hydroxy-2-Decenoic Acid in Royal Jelly Extract Induced Both Filaggrin and Amino Acid in a Cultured Human Three-Dimensional Epidermis Model

open access: yesCosmetics, 2017
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj   +1 more source

The Importance of Hydration in Wound Healing: Reinvigorating the clinical perspective [PDF]

open access: yes, 2016
Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist wound healing environment actively supports the healing response when compared to a dry ...
Atiyeh B.S.   +14 more
core   +1 more source

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