Results 41 to 50 of about 46,479 (310)

Different populations of pig epidermal cells: isolation and lipid composition.

open access: yesJournal of Lipid Research, 1975
Preparations representing populations of (a) basal and spinous cells, (b) granular cells, and (c) stratum corneum cells were obtained by successive treatments of epidermal slices from pig skin with dilute buffered trypsin solutions.
G M Gray, H J Yardley
doaj   +1 more source

Cytokine concentration across the stratum corneum in atopic dermatitis and healthy controls

open access: yesScientific Reports, 2020
Tape stripping is a promising technique for assessment of epidermal biomarkers in inflammatory skin diseases. However, to facilitate its implementation in the clinical practice, a thorough validation regarding sampling strategy is needed.
Maja-Lisa Clausen   +3 more
doaj   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

open access: yesAdvanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee   +21 more
wiley   +1 more source

SerpinB2 deficiency results in a stratum corneum defect and increased sensitivity to topically applied inflammatory agents

open access: yes, 2016
SerpinB2 (plasminogen activator inhibitor type 2) is constitutively expressed at high levels by differentiating keratinocytes in mice and humans; however, the physiological function of keratinocyte SerpinB2 remains unclear.
Nakaya, Helder I.   +23 more
core   +1 more source

Human stratum corneum lipids: characterization and regional variations

open access: yesJournal of Lipid Research, 1983
The lipids of mammalian stratum corneum are known to be important regulators of skin permeability. Since the human stratum corneum displays remarkable regional variations in skin permeability, we assessed the total lipid concentration, the distribution ...
M A Lampe   +6 more
doaj   +1 more source

Mimicking Human Perspiration: A Layered Microfluidic Skin Phantom With Tunable Hydrodynamics

open access: yesAdvanced Materials Interfaces, EarlyView.
A multilayer microfluidic skin phantom based on thermoplastic elastomers is developed to mimic human perspiration. Spatially controlled wettability enables capillary‐driven transport and controlled droplet formation at the surface, resembling sweat gland behavior.
Chunyu Yang   +5 more
wiley   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

Status of surfactants as penetration enhancers in transdermal drug delivery

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical preparations. In recent years, surfactants have been employed to enhance the permeation rates of several drugs via transdermal route.
Iti Som, Kashish Bhatia, Mohd. Yasir
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

An In vivo Comparison of Biomimetic vs. Traditional Skin Moisturization [PDF]

open access: yes, 2015
The aim of this study was to determine whether a biomimetic cream can deliver superior moisturisation to the skin of human volunteers aged over 60, compared to the effects of a conventional moisturiser containing high levels of petrolatum and mineral oil.
Kurimo, Ritva   +3 more
core  

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