Results 61 to 70 of about 87,981 (309)
Effect of different thickness of keratin layer of ductus papillaris on state of parenchyma in cow udder [PDF]
Veterinarski Glasnik, 2011 Ductus papillaris presents the frontline of defense of the mammary gland against the penetration of microorganisms into the milk cystern and the mammary gland parenchyma.
Davidov Ivana +4 more
doaj +1 more source
Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery
Pharmaceutics, 2023 Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of ...
Luca Casula +10 more
doaj +1 more source
Advanced Science, EarlyView.A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee +9 more
wiley +1 more source
MetabolitesBackground: Sensitive skin exhibits impaired skin barrier function. The lipid composition of the skin, a pivotal element within the stratum corneum’s “brick-and-mortar” structure, plays a dual role: it is integral to cell differentiation processes and ...
Agui Xie +3 more
doaj +1 more source
The physics of stratum corneum lipid membranes [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2016 The stratum corneum (SC), the outermost layer of skin, comprises rigid corneocytes (keratin-filled dead cells) in a specialized lipid matrix. The continuous lipid matrix provides the main barrier against uncontrolled water loss and invasion of external pathogens.
Das, C, Olmsted, PD
openaire +5 more sources
Temperature dependence of water content of stratum corneum [PDF]
, 1975 The water content of human stratum corneum has been measured gravimetrically in vitro in relation to relative humidity (RH) and temperature. Water content increased with increasing RH.
H.E. JONES +7 more
core +1 more source
Advanced Science, EarlyView.An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu +7 more
wiley +1 more source
In vivo human skin penetration of (–)-epigallocatechin-3-gallate from topical formulations
Acta Pharmaceutica, 2014 The aim of the study was to examine the effect of topical vehicles on the in vivo human stratum corneum penetration of the antioxidant and skin photoprotective agent (-)-epigallocatechin-3-gallate (EGCG).
Scalia Santo +2 more
doaj +1 more source
DNase 2 is the main DNA-degrading enzyme of the stratum corneum [PDF]
, 2011 The cornified layer, the stratum corneum, of the epidermis is an efficient barrier to the passage of genetic material, i.e. nucleic acids. It contains enzymes that degrade RNA and DNA which originate from either the living part of the epidermis or from ...
Torriglia Alicia +23 more
core +2 more sources
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source