Results 61 to 70 of about 46,479 (310)
MetabolitesBackground: Sensitive skin exhibits impaired skin barrier function. The lipid composition of the skin, a pivotal element within the stratum corneum’s “brick-and-mortar” structure, plays a dual role: it is integral to cell differentiation processes and ...
Agui Xie +3 more
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Antioxidants, 2020 Anthocyanins are natural colorants with antioxidant properties, shown to inhibit photoaging reactions and reduce symptoms of some skin diseases. However, little is known about their penetration through the stratum corneum, a prerequisite for bioactivity.
Alexandra Westfall +3 more
doaj +1 more source
Impact of Alkanediols on Stratum Corneum Lipids and Triamcinolone Acetonide Skin Penetration
Pharmaceutics, 2021 Alkanediols are widely used as multifunctional ingredients in dermal formulations. In addition to their preservative effect, considering their possible impact on drug penetration is also essential for their use.
Melanie Sigg, Rolf Daniels
doaj +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
, 2020 Stratum corneum (SC) prevents evaporation of internal moisture and maintains dermal flexibility and fluidity. Malnutrition is known to decrease SC hydration, but involvement of nutritional status in SC hydration of dialysis patients is unclear.
Nozawa, Yuko +34 more
core +1 more source
Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum
Acta Dermato-Venereologica, 2018 Previously, a skin barrier repair model was developed to examine the effect of formulations on the lipid properties of compromised skin. In this model, the lipid organization mimics that of several skin diseases with impaired skin barrier and less dense ...
Tineke Berkers +3 more
doaj +1 more source
In vivo human skin penetration of (–)-epigallocatechin-3-gallate from topical formulations
Acta Pharmaceutica, 2014 The aim of the study was to examine the effect of topical vehicles on the in vivo human stratum corneum penetration of the antioxidant and skin photoprotective agent (-)-epigallocatechin-3-gallate (EGCG).
Scalia Santo +2 more
doaj +1 more source
An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring
Advanced Science, EarlyView.This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal +9 more
wiley +1 more source
Elucidating the molecular landscape of the stratum corneum
, 2022 • Characterization of the molecular structure of skin, especially the barrier layer, the stratum corneum using 3D OrbiSIMS. • Understand the chemical variations relating to fundamental biological processes, such as the epidermal cholesterol sulfate ...
Alexander, Morgan R. +11 more
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Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction
Journal of Lipid Research, 1998 The barrier function of the skin resides in the stratum corneum (SC). This outermost layer consists of protein-rich corneocytes and lipid-rich intercellular domains.
G.S.K. Pilgram +4 more
doaj +1 more source