Results 71 to 80 of about 46,670 (310)

TrichomeLess Regulator 3 is required for trichome initial and cuticle biosynthesis in Artemisia annua

open access: yesMolecular Horticulture
Artemisinin is primarily synthesized and stored in the subepidermal space of the glandular trichomes of Artemisia annua. The augmentation of trichome density has been demonstrated to enhance artemisinin yield.
Boran Dong   +7 more
doaj   +1 more source

Utilizing Untargeted Lipidomics Technology to Elucidate Differences in Lipid Compositions Among Sensitive Dry, Sensitive Oily and Healthy Skin Types

open access: yesMetabolites
Background: Sensitive skin exhibits impaired skin barrier function. The lipid composition of the skin, a pivotal element within the stratum corneum’s “brick-and-mortar” structure, plays a dual role: it is integral to cell differentiation processes and ...
Agui Xie   +3 more
doaj   +1 more source

Ex Vivo and In Vivo Assessment of the Penetration of Topically Applied Anthocyanins Utilizing ATR-FTIR/PLS Regression Models and HPLC-PDA-MS

open access: yesAntioxidants, 2020
Anthocyanins are natural colorants with antioxidant properties, shown to inhibit photoaging reactions and reduce symptoms of some skin diseases. However, little is known about their penetration through the stratum corneum, a prerequisite for bioactivity.
Alexandra Westfall   +3 more
doaj   +1 more source

Impact of Alkanediols on Stratum Corneum Lipids and Triamcinolone Acetonide Skin Penetration

open access: yesPharmaceutics, 2021
Alkanediols are widely used as multifunctional ingredients in dermal formulations. In addition to their preservative effect, considering their possible impact on drug penetration is also essential for their use.
Melanie Sigg, Rolf Daniels
doaj   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

open access: yesAdvanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao   +3 more
wiley   +1 more source

Cell Layer and Density of Negro and Caucasian Stratum Corneum [PDF]

open access: yes, 1974
Stratum corneum from Negroes and Caucasians has been compared with respect to facility of tape stripping, numbers of cell layers, and density. Significantly more strips were required for removal of stratum corneum, and significantly more cell layers were
Weigand, Dennis Allen   +2 more
core   +1 more source

Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum

open access: yesActa Dermato-Venereologica, 2018
Previously, a skin barrier repair model was developed to examine the effect of formulations on the lipid properties of compromised skin. In this model, the lipid organization mimics that of several skin diseases with impaired skin barrier and less dense ...
Tineke Berkers   +3 more
doaj   +1 more source

In vivo human skin penetration of (–)-epigallocatechin-3-gallate from topical formulations

open access: yesActa Pharmaceutica, 2014
The aim of the study was to examine the effect of topical vehicles on the in vivo human stratum corneum penetration of the antioxidant and skin photoprotective agent (-)-epigallocatechin-3-gallate (EGCG).
Scalia Santo   +2 more
doaj   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

open access: yesAdvanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang   +10 more
wiley   +1 more source

X-ray Diffraction Analysis of Stratum Corneum Membrane Couplets [PDF]

open access: yes, 1983
X-ray diffraction analysis was done on the membrane couplets isolated from newborn mouse stratum corneum. The same lipid reflections were observed for whole stratum corneum and couplets, adding further support to the thesis that stratum corneum lipid is ...
Bonar, Laurence   +3 more
core   +1 more source

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