Results 71 to 80 of about 87,981 (309)

Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum

open access: yesActa Dermato-Venereologica, 2018
Previously, a skin barrier repair model was developed to examine the effect of formulations on the lipid properties of compromised skin. In this model, the lipid organization mimics that of several skin diseases with impaired skin barrier and less dense ...
Tineke Berkers   +3 more
doaj   +1 more source

Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction

open access: yesJournal of Lipid Research, 1998
The barrier function of the skin resides in the stratum corneum (SC). This outermost layer consists of protein-rich corneocytes and lipid-rich intercellular domains.
G.S.K. Pilgram   +4 more
doaj   +1 more source

Microfluidic-enabled liposomes elucidate size-dependent transdermal transport. [PDF]

open access: yesPLoS ONE, 2014
Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles.
Renee R Hood   +6 more
doaj   +1 more source

The surface structure of the stratum corneum

open access: yesActa Dermato-Venereologica, 1972
No abstract ...
R, Marks, T, Saylan
openaire   +2 more sources

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

open access: yesAdvanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao   +9 more
wiley   +1 more source

Half-mast dew point and winter-beaten stratum corneum. [PDF]

open access: yes, 2014
peer reviewedThe frontier between the human body and the environment is largely represented by the stratum corneum. It is obvious that the skin aspect on some body sites appears dry and rough in some predisposed individuals during winter season.
PIERARD, Gérald   +2 more
core  

Tissue binding affects the kinetics of theophylline diffusion through the stratum corneum barrier layer of skin

open access: yes, 2011
Tissue binding affects the kinetics of theophylline diffusion through the stratum corneum barrier layer of ...
H. Frederick Frasch   +6 more
core   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing   +9 more
wiley   +1 more source

Electrical properties of the epidermal stratum corneum

open access: yesMedical & Biological Engineering, 1976
The electrical properties of the epidermal stratum corneum were investigated by cellulose adhesive tape stripping. The distribution function of the relaxation times on the impedance locus of stratum corneum was deduced. It was found that this function of the thin layer does not satisfy the Cole-Cole circular arc, but the skin impedance remaining after ...
YAMAMOTO, Tatsuma, YAMAMOTO, Yoshitake
openaire   +3 more sources

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma   +14 more
wiley   +1 more source

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