Results 91 to 100 of about 87,981 (309)

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source

Can nano-hydroxyapatite permeate the oral mucosa? A histological study using three-dimensional tissue models.

PLoS ONE, 2019
Nano-hydroxyapatite is used in oral care products worldwide. But there is little evidence yet whether nano-hydroxyapatite can enter systemic tissues via the oral epithelium.
Shogo Komiyama, Ryosuke Miyasaka, Keiichiro Kikukawa, Roslyn Hayman   +3 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Morphological description of the oropharyngeal cavity of Kinosternon scorpioides scorpioides (Linnaeus, 1766), (Testudines: Kinosternidae)

The Anatomical Record, EarlyView.
Gross morphology, Light Microscopy and Scanning Electron Microscopy revealed the structural organization of the oropharyngeal cavity of Kinosternon scorpioides scorpioides, characterized by mucous epithelium, epithelial pores, and developed lingual papillae.
Andréa Magalhães Bezerra, Diego Ferreira de Sousa, Luane Botelho, André Luís Nogueira Lima, Érika Branco, Elane Guerreiro Giese, Washington Luís Pereira, Ana Rita de Lima   +7 more
wiley   +1 more source

Body Mass Index z Scores Correlate with Epidermal Function in Chinese Children

Diabetes, Metabolic Syndrome and Obesity, 2023
Bin Yang,1,* Qingsong Lai,2,* Aiqi Chen,2 Li Ye,1 Xiaohua Wang,1 Yulin Lai,2 Dan Liu,3 Mao-Qiang Man3 1Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou City, Guangdong, 510091, People’s Republic of China ...
Yang B, Lai Q, Chen A, Ye L, Wang X, Lai Y, Liu D, Man MQ   +7 more
doaj  

Mechanism investigation of ethosomes transdermal permeation

International Journal of Pharmaceutics: X, 2019
Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear.
Xiao-Qian Niu, Dan-Ping Zhang, Qiong Bian, Xing-Fu Feng, Hao Li, Yue-Feng Rao, Yong-Mei Shen, Fu-Neng Geng, An-Ran Yuan, Xiao-Ying Ying, Jian-Qing Gao   +10 more
doaj   +1 more source

Role Of Stratum Corneum Lipids As Moisture Retaining Agent

, 1987
The water holding ability of the stratum corneum is related to the bilayer structured epidermal lipids by comparison of these lipids with the lamellar liquid crystal of free fatty acid/soap/water.
Osborne, David W., Friberg, Stig
core   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Ceramides metabolism and impaired epidermal barrier in cutaneous diseases and skin aging: focus on the role of the enzyme PNPLA1 in the synthesis of ω-O-acylceramides and its pathophysiological involvement in some forms of congenital ichthyoses☆

Oilseeds and fats, crops and lipids, 2019
The outermost layer of the skin, the stratum corneum, is essential for the protective barrier functions of the skin. It results from the stacking of corneocytes, the dead flattened cells resulting from epidermal terminal differentiation of underlying ...
Jonca Nathalie
doaj   +1 more source

Infant skin-cleansing product versus water : a pilot randomized, assessor-blinded controlled trial [PDF]

, 2011
Background The vulnerability of newborn babies' skin creates the potential for a number of skin problems. Despite this, there remains a dearth of good quality evidence to inform practice.
Anna Hart, Michael J Cork, Cook, M, Tina Lavender, Hart, A., Hart Anna, Bedwell Carol, Bedwell, C., Cork, Michael J., Ediri O'Brien, Lavender, T., Turner Mark, Carol Bedwell, O'Brien Ediri, Lavender Tina, Cork Michael J, Lavender, Tina, Mark Turner, Hart, Anna, Turner, Mark, O'Brien, Ediri, Turner, M., Bedwell, Carol, O'Brien, E, O'Brien, E., Cork, M.J.   +25 more
core   +2 more sources