Results 51 to 60 of about 46,479 (310)

Light confinement in stratum corneum

open access: yes, 2023
The epidermis is the outermost layer of the skin, and it plays a crucial role in protecting the body from external insults such as UV radiation and physical trauma.
Saiko, Gennadi
core  

Amino acids disrupt calcium-dependent adhesion of stratum corneum.

open access: yesPLoS ONE, 2019
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation in
Jin-Hyun Kim   +7 more
doaj   +1 more source

Structure Enhancement Relationship of Chemical Penetration Enhancers in Drug Transport across the Stratum Corneum

open access: yesPharmaceutics, 2012
The stratum corneum is a major barrier of drug penetration across the skin in transdermal delivery. For effective transdermal drug delivery, skin penetration enhancers are used to overcome this barrier.
Doungdaw Chantasart, S. Kevin Li
doaj   +1 more source

Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery

open access: yesPharmaceutics, 2023
Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of ...
Luca Casula   +10 more
doaj   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

Thermomechanical Analysis of Stratum Corneum II. Application

open access: yes, 1972
The viscoelastic and dimensional properties of human stratum corneum as probed by thermomechanical analysis differ significantly from the previously reported data for newborn rat corneum with respect to temperature and degree of several thermally induced
Humphries, William T.   +1 more
core   +1 more source

Effect of different thickness of keratin layer of ductus papillaris on state of parenchyma in cow udder [PDF]

open access: yesVeterinarski Glasnik, 2011
Ductus papillaris presents the frontline of defense of the mammary gland against the penetration of microorganisms into the milk cystern and the mammary gland parenchyma.
Davidov Ivana   +4 more
doaj   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

open access: yesAdvanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao   +6 more
wiley   +1 more source

Hyaluronan Exists in the Normal Stratum Corneum

open access: yes, 2000
Hyaluronan is well known to exist as a water-sorbed macromolecule in the extracellular matrix. We here examined whether hyaluronan exists in the normal stratum corneum. High performance liquid chromatography was used to quantify hyaluronan content in the
Inoue, Shintaro   +4 more
core   +1 more source

TrichomeLess Regulator 3 is required for trichome initial and cuticle biosynthesis in Artemisia annua

open access: yesMolecular Horticulture
Artemisinin is primarily synthesized and stored in the subepidermal space of the glandular trichomes of Artemisia annua. The augmentation of trichome density has been demonstrated to enhance artemisinin yield.
Boran Dong   +7 more
doaj   +1 more source

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