Results 51 to 60 of about 46,670 (310)
Cytokine concentration across the stratum corneum in atopic dermatitis and healthy controls
Scientific Reports, 2020 Tape stripping is a promising technique for assessment of epidermal biomarkers in inflammatory skin diseases. However, to facilitate its implementation in the clinical practice, a thorough validation regarding sampling strategy is needed.
Maja-Lisa Clausen +3 more
doaj +1 more source
Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue
Advanced Materials Technologies, EarlyView.Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan +10 more
wiley +1 more source
Lipid Thermotropic Transitions in Human Stratum Corneum [PDF]
, 1986 The techniques of differential scanning calorimetry (DSC) and thermal perturbation infrared (IR) spectrometry were used to investigate thermal transitions in intact, fractionated, and lipid-extracted human stratum corneum.
Golden, Guia M +4 more
core +1 more source
Human stratum corneum lipids: characterization and regional variations
Journal of Lipid Research, 1983 The lipids of mammalian stratum corneum are known to be important regulators of skin permeability. Since the human stratum corneum displays remarkable regional variations in skin permeability, we assessed the total lipid concentration, the distribution ...
M A Lampe +6 more
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
A population-based study of the stratum corneum moisture [PDF]
, 2016 Thiago de Farias Pires,1 Ana Paula Azambuja,2 Andrea Roseli Vançan Russo Horimoto,1 Mary Sanae Nakamura,2 Rafael de Oliveira Alvim,1 José Eduardo Krieger,1 Alexandre Costa Pereira1 1Laboratory of Genetics and Molecular Cardiology, Heart ...
Pires TF +6 more
core
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
Advanced Science, EarlyView.In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Cholesteatoma:a morphologic study of stratum corneum lipids [PDF]
, 2001 Two different lipid-retaining fixation techniques permitted electron microscopic visualization of both intra- and extracellular lipids in cholesteatoma epithelium obtained from 25 patients.
Halkierø-Sørensen, L. +3 more
core +1 more source
Status of surfactants as penetration enhancers in transdermal drug delivery
Journal of Pharmacy and Bioallied Sciences, 2012 Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical preparations. In recent years, surfactants have been employed to enhance the permeation rates of several drugs via transdermal route.
Iti Som, Kashish Bhatia, Mohd. Yasir
doaj +1 more source
Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery
Pharmaceutics, 2023 Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of ...
Luca Casula +10 more
doaj +1 more source