In Vivo and Ex Vivo Evaluation of a Novel Method for Topical Delivery of Macromolecules Through the Stratum Corneum for Cosmetic Applications. [PDF]
Moradi A +4 more
europepmc +1 more source
ABSTRACT Background Daylight photodynamic therapy (DL‐PDT) has been combined with transepidermal drug delivery (TED) techniques to enhance photosensitizer penetration. Although studies have suggested improved clinical and histological outcomes with DL‐PDT combined with ablative laser, evidence regarding carcinogenesis and dermal remodeling markers ...
Camila de Oliveira Bento +5 more
wiley +1 more source
Correlations between Skin Condition Parameters and Ceramide Profiles in the Stratum Corneum of Healthy Individuals. [PDF]
Akiyama F +6 more
europepmc +1 more source
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
wiley +1 more source
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source
Erratum: Effect of transdermal drug delivery patches on the stratum corneum: in vivo inspection with a handheld terahertz probe: publisher's note. [PDF]
Hernandez-Serrano AI +5 more
europepmc +1 more source
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang +10 more
wiley +1 more source
Permeation dynamics of microemulsions according to the amount of deep eutectic solvent when applied to the stratum corneum. [PDF]
Shinoda S, Tanigawa M, Sakuragi M.
europepmc +1 more source
A thermoreversible gelatin‐based gel forms a soft, conformal bioelectronic interface on complex biological surfaces. The flowable precursor penetrates hair‐dense regions, solidifies in situ, and maintains low impedance through adaptive contact and hydration retention.
Ruinan Hao +9 more
wiley +1 more source
Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases. [PDF]
Choi EH, Kang H.
europepmc +1 more source

