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Polymorphism in stratum corneum lipids

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1994
Fourier transform infrared spectroscopy (FTIR) was employed to investigate the thermotropic phase behavior of stratum corneum lipid multilamellae. Stratum corneum (SC), the uppermost layer of mammalian skin, is unusual in many respects. It has been demonstrated that the lipids of the stratum corneum provide the primary electrical and transport ...
B, Ongpipattanakul   +2 more
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Stratum corneum Lipid Function

Dermatologica, 2009
The stratum corneum contains a complex mixture of polar and nonpolar lipids in its intercellular spaces. These lipids, present in form of multiple lamellae, have been investigated for their role in providing the epidermal barrier to transcutaneous water loss, the selective barrier from the inside to the outside of the organism and partly the process of
N Y, Schürer, G, Plewig, P M, Elias
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The stratum corneum: a double paradox

Journal of Cosmetic Dermatology, 2008
SummaryThe stratum corneum (SC) (i.e., the outermost layer of human skin) is a complex and paradoxical tissue composed of corneocytes and a matrix of intercellular lipids playing an essential role as the skin's protective barrier. The first paradox of SC is its dual nature.
Anne, Pouillot   +4 more
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A distinct stratum corneum antigen in psoriasis and its reactions with stratum corneum autoantibodies

APMIS, 1992
Stratum corneum antibodies are ubiquitous and can be detected by various immunological methods. Of these, the ones detected by hemagglutination undergo changes in antibody titers and have been implicated in psoriasis. The purpose of our study was to examine if differences exist in the activities of the antigens isolated from psoriatic scales in ...
S S, Qutaishat   +3 more
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The Antioxidant Network of the Stratum corneum

2000
Many studies have demonstrated beneficial health effects of topical antioxidant application; however, the underlying mechanisms are not well understood. To better understand the protective mechanism of oxogenous anti-oxidants, it is important to clarify the physiological distribution, activity and regulation of antioxidants. Also, the generation of ROS
J J, Thiele   +4 more
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Stratum Corneum Maturation

Skin Pharmacology and Physiology, 2004
The importance of the stratum corneum and its barrier function for infants, especially for newborns, is clinically evident. Research regarding the maturation of the stratum corneum in neonates, i.e. when full barrier function is obtained, has produced varying results.
Y.B. Chiou, U. Blume-Peytavi
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The skin surface and stratum corneum

British Journal of Dermatology, 1990
In senescence, marked changes occur on the surface of the skin and in the stratum corneum. One of the most important features is the reduced quantity of hydrolipid emulsion on the skin surface. This has to be taken into account when developing skin care for the elderly.
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Separation of Stratum Corneum

British Journal of Dermatology, 1972
A, Gafoor, K M, Townsend
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[The stratum corneum].

Annales de dermatologie et de venereologie, 2002
Epidermal differentiation is a continuous process, constituting and renewing a protective layer at the skin surface: the stratum corneum, composed of cornified keratinocytes that is a barrier to water diffusion. Massive loss of physiologic liquids is one of the severest consequences of extensive burns.
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Protein degradation in the stratum corneum

International Journal of Cosmetic Science
AbstractThe stratum corneum (SC), the outermost epidermal layer, plays a pivotal role in skin barrier function. This review delves into the intricate process of protein degradation within the stratum corneum, elucidating the roles of specific enzymes, regulatory mechanisms and the consequent impact on various skin conditions.
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