Results 61 to 70 of about 682,980 (296)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Microstructure and strength of metals processed by severe plastic deformation [PDF]
, 2006 The microstructure of f.c.c. metals (Al, Cu, Ni) and alloys (Al-Mg) processed by severe plastic deformation (SPD) methods is studied by X-ray diffraction line profile analysis.
Chinh, Nguyen Quang +3 more
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Boards as an Accountability Mechanism [PDF]
, 2014 Boards are central to the system of nonprofit accountability, but their adequacy has been increasingly questioned by policymakers, media, researchers and others.
Ostrower, Francie Dr.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Research and application progress of high entropy alloy materials in laser additive repair
Journal of Aeronautical MaterialsIntroducing emerging high entropy alloys materials into advanced intelligent manufacturing for laser additive repair is expected to promote the deep integration of new generation of materials and manufacturing technology and greatly improve the ...
LI Zhanming +4 more
doaj +1 more source
Characterization of strain-induced precipitation in Inconel 718 superalloy [PDF]
, 2016 © 2016 ASM International Inconel 718 presents excellent mechanical properties at high temperatures, as well as good corrosion resistance and weldability.
Cabrera Marrero, José M. +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Analysis of FRP shear strengthening solutions for reinforced concrete beams considering debonding failure [PDF]
, 2016 In this paper, a fiber beam model previously developed by the authors for the nonlinear analysis of strengthened elements, including the effects of shear, is used to predict the response of reinforced concrete (RC) beams strengthened in shear with fiber ...
Bairán García, Jesús Miguel +3 more
core +2 more sources