Results 61 to 70 of about 525,011 (295)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
LEADERSHIP VERSUS MANAGEMENT IN DESIGN AND BUSINESS CONSULTANCY COMPANIES [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2017 In this paper it was developed a comparative approach of the two concepts that refer to the management sphere: management and leadership, trying to emphasize the similarities and differences that exist between them.
Stejărel BREZULEANU +3 more
doaj
MEMILIH PEMIMPIN DALAM PRAKTIK KEPEMIMPINAN ORGANISASI SEKOLAH DI ERA GLOBAL
Informasi, 2013 The leader and leadership courses have produced many hypotheses which haven’t been solved from time to time. With regard to the demands of the globalization era recently, the successful organizations are those which are ruled by figures who have ...
Sunarta sunarta
doaj +1 more source
What Helps Leaders Grow: Highlights from the Fund for Leadership Advancement [PDF]
, 2009 Executive directors are as unique as the nonprofits they lead. And the leadership needs of their organizations vary over time -- as different points in the life of a nonprofit call for different competencies. The most effective leaders continually assess
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Faith as competitive strategy: The value-based leadership advantage in Christian hospitals
South African Journal of Economic and Management SciencesBackground: Christian foundation private hospitals in Indonesia must navigate a challenging healthcare environment characterised by limited resources, regulatory requirements and rising patient expectations while maintaining their religious identity in a
Kristiana Susilowati +2 more
doaj +1 more source
Economic Development Potential Of The Krakow Region [PDF]
, 2007 Analyzing economic development potential and activities in a region requires identifying factors essential for a successful strategy and analyzing the locale in terms of its resources and relative position within a broader economic environment.
Boryczko, Alicja
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source