Results 71 to 80 of about 2,464,725 (290)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The system in the room. The extent to which coaching can change the organization [PDF]
, 2008 Synopsis: In this book, each contributor describes the way they use the systemic model in their consultancy practice. Their key ideas are illustrated via a case example (or examples), where possible including detailed accounts of the exercises and ...
Huffington, Clare
core
Frontiers in PsychologyIn the present study, we explored the relationship between proactive personality and career adaptability to construct a cross-level moderated mediation model based on the conservation of resources (COR) theory. By conducting a time-lagged study involving
Hui Li, Ziyue Xu, Suhao Song, Hui Jin
doaj +1 more source
A structural model of job resources, organisational and individual strengths use and work engagement
SA Journal of Industrial Psychology, 2014 Orientation: Organisations will not be able to maintain a competitive advantage by merely focusing on the development of their employees’ weaknesses. Employees should also be provided with sufficient job resources and opportunities to develop and use ...
Cheri Botha, Karina Mostert
doaj +1 more source
Serious Games in Cultural Heritage [PDF]
, 2009 Although the widespread use of gaming for leisure purposes has been well documented, the use of games to support cultural heritage purposes, such as historical teaching and learning, or for enhancing museum visits, has been less well considered.
Anderson, Eike F. +5 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
SA Journal of Industrial Psychology, 2017 Orientation: It is well known that the first year at university can be very challenging and stressful for students. While some students mainly depend on the university to assist them through this time, other students want to proactively manage this ...
Karina Mostert +2 more
doaj +1 more source
, 2017 In this work, we have characterized changes in the dynamics of a two-dimensional relativistic standard map in the presence of dissipation and specially when it is submitted to thermal effects modeled by a Gaussian noise reservoir.
Albuquerque, Holokx A. +2 more
core +1 more source
Automated Strength-Interval Curve Generation Using Actors
Computer Methods and Programs in BiomedicineStrength-interval (SI) curves are used by physiologists to quantify the response of excitable tissue as a function of the strength and timing of an electrical stimulus. In the context of cardiac electrophysiology, SI curves characterize the refractoriness of cardiac tissue as a function of inter-stimulus interval length.
Raymond J. Spiteri +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source