Results 131 to 140 of about 326,708 (370)

Layer guided-acoustic plate mode biosensors for monitoring MHC-peptide interactions [PDF]

open access: yes, 2006
The transduction signals from the immobilisation of a class I heavy chain, HLA-A2, on a layer guided acoustic plate mode device, followed by binding of beta(2)-microglobulin and subsequent selective binding of a target peptide are ...
Dodi, I. A.   +7 more
core   +1 more source

Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance

open access: yesAdvanced Materials, EarlyView.
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee   +14 more
wiley   +1 more source

Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum. [PDF]

open access: yes, 2019
We previously showed that Entamoeba histolytica kills human cells through a mechanism that we termed trogocytosis ("trogo-" means "nibble"), due to its resemblance to trogocytosis in other organisms. In microbial eukaryotes like E.
Miller, Hannah W   +2 more
core   +1 more source

Transparent Temperature Sensors for Photothermal Neuromodulation: Advances, Challenges, and Future Directions

open access: yesAdvanced Materials Interfaces, EarlyView.
Photothermal neuromodulation is a promising technique for versatile neural signal study and treatment development. To further develop these technologies and optimize their effectiveness, transparent electrical temperature sensors with high thermal sensitivity and resolution are essential for accurately monitoring temperature changes during ...
Jee Woong Lee   +7 more
wiley   +1 more source

Novel platform for engineering stable and effective vaccines against botulinum neurotoxins A, B and E

open access: yesFrontiers in Immunology
Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is the most toxic protein known, capable of causing severe paralysis and posing a significant bioterrorism threat due to its extreme lethality even in minute quantities.
Yang Liu   +6 more
doaj   +1 more source

Ku80 cooperates with CBP to promote COX-2 expression and tumor growth. [PDF]

open access: yes, 2015
Cyclooxygenase-2 (COX-2) plays an important role in lung cancer development and progression. Using streptavidin-agarose pulldown and proteomics assay, we identified and validated Ku80, a dimer of Ku participating in the repair of broken DNA double ...
Chen, Yiming   +23 more
core   +3 more sources

Antifouling PEG Coatings by Thiol‐Acrylate Conjugate Addition Reactions for Generation of Protein Patterns via Photobleaching‐Induced Protein Binding (PiPB) BioBitmaps Using Maskless Projection Lithography

open access: yesAdvanced Materials Interfaces, EarlyView.
Homo‐bifunctional PEG, acrylate‐PEG‐acrylate (PEGDA), coatings are prepared on glass and glass‐type surfaces using solvent‐free thiol‐acrylate conjugate addition reactions at room temperature. The prepared PEGDA coatings are stable, antifouling, and provide feature terminal acrylates that can act as free radical acceptors for photobleaching‐induced ...
Ali Usama   +11 more
wiley   +1 more source

Endogenous biotin-binding proteins: an overlooked factor causing false positives in streptavidin-based protein detection

open access: yesMicrobial Biotechnology, 2014
Biotinylation is widely used in DNA, RNA and protein probing assays as this molecule has generally no impact on the biological activity of its substrate.
Hanne L. P. Tytgat   +6 more
semanticscholar   +1 more source

Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1 [PDF]

open access: yes, 2011
We describe the use of iterative in situ click chemistry to design an Akt-specific branched peptide triligand that is a drop-in replacement for monoclonal antibodies in multiple biochemical assays.
Agnew, Heather D.   +12 more
core   +2 more sources

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

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