Results 181 to 190 of about 323,420 (331)

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Advancing Lateral Flow Detection in CRISPR/Cas12a Systems Through Rational Understanding and Design Strategies of Reporter Interactions. [PDF]

Biosensors (Basel)
Safenkova IV, Kamionskaya MV, Sotnikov DV, Biketov SF, Zherdev AV, Dzantiev BB.   +5 more
europepmc   +1 more source

Highly efficient purification of protein complexes from mammalian cells using a novel streptavidin‐binding peptide and hexahistidine tandem tag system: Application to Bruton's tyrosine kinase [PDF]

, 2010
Yifeng Li, Sarah Franklin, Michael J. Zhang, Thomas M. Vondriska   +3 more
openalex   +1 more source

Site-specific strategies stylize streptavidin [PDF]

Nature Biotechnology, 1995
openaire   +2 more sources

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Biotin methyl ester enhances cargo release in RUSH system and enables rapid biotinylation with TurboID. [PDF]

Commun Biol
Uehara T, Takiguchi A, Tojima T, Nakano A, Kagawa S, Nehira T, Satoh T, Satoh AK.   +7 more
europepmc   +1 more source

A biotin-streptavidin-biotin bridge dramatically enhances cell fusion

, 2014
Jinhua Li, Xianzhong Yu, Thomas E. Wagner, Yanzhang Wei   +3 more
openalex   +2 more sources

Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibody [PDF]

, 1995
Damian Marshall, RB Pedley, RG Melton, JA Boden, R Boden, RHJ Begent   +5 more
openalex   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Protocol for identification of cell-surface proteins with horseradish peroxidase. [PDF]

STAR Protoc
Wu L, Pandey V, Wohlschlegel JA, Khakh BS.   +3 more
europepmc   +1 more source