Results 51 to 60 of about 93,238 (289)

EFFECTS OF BACTERIAL LIGANDS OF PATTERN-RECOGNIZING RECEPTORS (PRR) ON MONOCYTE-LIKE THP-1 CELLS UPON THEIR TRANSENDOTHELIAL MIGRATION

Медицинская иммунология, 2014
. The aim of study was to compare the influence of lipopolysaccharide (LPS) component from Gram-negative bacteria (E. coli 055:B5), and a lysate of Gram-positive bacterium (Streptococcus pyogenes, type M1, strain 40/58) upon transendothelial migration ...
E. P. Starikova, D. I. Sokolov, L. A. Burova, S. A. Sel’kov, I. S. Freidlin   +4 more
doaj   +1 more source

Streptococcus salivarius 24SMBc Genome Analysis Reveals New Biosynthetic Gene Clusters Involved in Antimicrobial Effects on Streptococcus pneumoniae and Streptococcus pyogenes

Microorganisms, 2022
Streptococcus salivarius 24SMBc is an oral probiotic with antimicrobial activity against the otopathogens Streptococcus pyogenes and Streptococcus pneumoniae. Clinical studies have reinforced its role in reducing the recurrence of upper respiratory tract
Gaia Vertillo Aluisio, Ambra Spitale, Luca Bonifacio, Grete Francesca Privitera, Aldo Stivala, Stefania Stefani, Maria Santagati   +6 more
doaj   +1 more source

Coinfection of Leishmania (Viannia) braziliensis and Streptococcus pneumoniae in multiple cutaneous lesions [PDF]

, 2016
Key learning points Cutaneous leishmaniasis is the most common clinical disease caused by all the Leishmania species that are pathogenic to humans. Other bacterial coinfections of Leishmania lesions have been described, but this is the first report of ...
Chiapello, Laura Silvina, Cortes, Paulo R., De Petris, Carlos, Dib, David, Echenique, Jose Ricardo, Herrero, Mónica V., Nuncira, Carmen T.   +6 more
core   +2 more sources

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

Biotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei, Sebastian Martewicz, Ramin Amiri, Meihua Cui, Nicola Elvassore, Camilla Luni   +5 more
wiley   +1 more source

Emergent Invasive Group A Streptococcus dysgalactiae subsp. equisimilis, United States, 2015–2018

Emerging Infectious Diseases, 2019
The term group A Streptococcus is considered synonymous for the species Streptococcus pyogenes. We describe an emergent invasive S. dysgalactiae subspecies equisimilis lineage that obtained the group A antigen through a single ancestral recombination ...
Sopio Chochua, Joy Rivers, Saundra Mathis, Zhongya Li, Srinivasan Velusamy, Lesley McGee, Chris Van Beneden, Yuan Li, Benjamin J. Metcalf, Bernard Beall   +9 more
doaj   +1 more source

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]

, 2020
Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A, Fellmann, Christof, Lew, Rachel J, McMahon, Blake, Shivram, Haridha, Watters, Kyle E   +5 more
core   +3 more sources

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved α-D-GlcNAc-β-1,4-L-rhamnosyltransferase [PDF]

, 2019
Group A carbohydrate (GAC) is a bacterial peptidoglycan-anchored surface rhamnose polysaccharide (RhaPS) that is essential for growth of Streptococcus pyogenes and contributes to its ability to infect the human host.
Albesa-Jové, Artimo, Azul Zorzoli, Benjamin H. Meyer, Bentley, Brandenburg, Breton, Breton, Brown, Bruyere, Caliot, Cartee, Chang, Chapot-Chartier, Charbonneau, Chia, Clarke, Coligan, Courtney, Cunningham, De, De Bruyn, Dhaked, Ding, Druzhinina, Dusan Uhrin, Edgar, Efstratiou, Elaine Adair, Endo, Ferretti, Franco, Guerin, Helge C. Dorfmueller, Henningham, Heymann, Hong, Huang, Hyams, Islam, Islam, James, Jankute, Jurtshuk, Kelley, Klena, Kovacs, Krause, Kristian, Lairson, Lancefield, Le Breton, Le Breton, Lehrer, Leonid L. Danilov, Letunic, Lombard, Magee, Marchler-Bauer, Martinez-Fleites, Mazmanian, McCarty, Michon, Mistou, Moreland, Nagata, Nelson, Nothaft, Ogura, Ozaki, Parsonage, Persson, Pradel, Pritchard, Rini, Ristl, Robinson, Rodriguez-Iturbe, Rubens, Rubirés, Rucker, Rush, Sadovskaya, Schäffer, Schägger, Sewell, Shelburne, Shibata, Sievers, Sika-Paotonu, Sims Sanyahumbi, St. Michael, Sutcliffe, Swoboda, Tsuda, van der Beek, van Hensbergen, van Sorge, Vetting, Viklund, Villegas, Vladimir I. Torgov, Vladimir V. Veselovsky, Waldo, Wang, Wang, Weidenmaier, Willis, Wittgens, Wollin, Zeleznick   +110 more
core   +2 more sources

Validation of Hexaplex Recombinase Polymerase Amplification Assay for the Detection of Carbapenemase Genes in Klebsiella pneumoniae Isolates From Pediatric Inpatients

Journal of Clinical Laboratory Analysis, EarlyView.
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon, Nuntaree Chaichanawongsaroj   +1 more
wiley   +1 more source

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. [PDF]

, 2019
Group A Streptococcus (GAS) is a human-specific pathogen that evades the host immune response through the elaboration of multiple virulence factors. Although many of these factors have been studied, numerous proteins encoded by the GAS genome are of ...
Campeau, Anaamika, Dehaini, Diana, Fang, Ronnie H, Gonzalez, David J, Greene, Trever, Holay, Maya, Lamsa, Anne, LaRock, Christopher N, Pogliano, Kit, Sands, Jenna S, Wei, Xiaoli, Wierzbicki, Igor H, Ying, Man, Zhang, Liangfang, Zuniga, Elina   +14 more
core