A fundamental challenge in medical microbiology is to characterize the dynamic protein–protein interaction networks formed at the host–pathogen interface.
Lotta J Happonen+11 more
semanticscholar +1 more source
Binding of Streptococcus pyogenes to laminin.
Some strains of Streptococcus pyogenes isolated from infected human tissues were shown to bind laminin, a major component of basement membranes. Binding of 125I-laminin to bacteria was time dependent and functionally irreversible. Of several unlabeled proteins tested in competition experiments, laminin and fibrinogen inhibited binding of the ...
Switalski LM+4 more
openaire +3 more sources
The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis
Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes.
Brihaspati Sigdel
doaj +1 more source
Anchoring of proteins to lactic acid bacteria [PDF]
The anchoring of proteins to the cell surface of lactic acid bacteria (LAB) using genetic techniques is an exciting and emerging research area that holds great promise for a wide variety of biotechnological applications. This paper reviews five different
A Hoick+66 more
core +1 more source
Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies
The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for
M. Laabei, David Ermert
semanticscholar +1 more source
Fulminant streptococcus pyogenes infection. [PDF]
Life-threatening infection due to Streptococcus pyogenes (? haemolytic streptococcus, Lancefield's group A) has become uncommon since the introduction of penicillin.1 2 3 Excluding the four cases reported here, the department of bacteriology at this hospital has seen only six cases of Str pyogenes bacteraemia in the past 10 years, and nationally the ...
L Henry+3 more
openaire +3 more sources
Protective vaccination in the horse against _Streptococcus equi_ with recombinant antigens [PDF]
_Streptococcus equi_ subspecies _equi_ (_S. equi_) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles.
Andrew Waller+6 more
core +1 more source
Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis
EndoS from Streptococcus pyogenes hydrolyzes the functionally important glycan on the Fc portion of IgG during infections in humans. In mice with IgG mediated immunity against the M1 protein on the bacteria, EndoS is a virulence factor.
A. Naegeli+7 more
semanticscholar +1 more source
Pneumococcus and the stress-gradient hypothesis: a trade-off links $R_0$ and susceptibility to co-colonization across countries [PDF]
Modern molecular technologies have revolutionized our understanding of bacterial epidemiology, but reported data across different settings remain under-integrated in common theoretical frameworks. Pneumococcus serotype co-colonization, caused by the polymorphic bacteria Streptococcus pneumoniae, has been increasingly investigated in recent years. While
arxiv
Evaluation of the effect of tyrothricin on beta-hemolytic streptococci in salva. Part I: The effect of salvia upon bacteria. Part II: Effect of tyrothricin on the New York 5 strain of Streptococcus pyogenes in saliva [PDF]
Part II of thesis by Brancato, Noyes, and Swift. Part I of thesis by Swift. Thesis (M.A.)--Boston UniversityThe antibacterial effect of saliva has been known for many years.
Brancato, Frank P.+2 more
core +1 more source