Results 41 to 50 of about 39,303 (298)

Comparison of peak serum C-reactive protein and hydroxybutyrate dehydrogenase levels in patients with acute myocardial infarction treated with alteplase and streptokinase [PDF]

open access: yes, 1997
Peak serum C-reactive protein concentrations were measured in 146 patients randomized to receive streptokinase, alteplase, or a combination of streptokinase and alteplase in the GUSTO-I trial.
Baardman, T. (Taco)   +6 more
core   +5 more sources

Hydrophobic residues in the D‐domain of a plasminogen‐binding M‐protein modulate α‐helicity, oligomerization, and surface anchoring in Streptococcus pyogenes

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract Human plasminogen (hPg) binding M‐protein (PAM) is a major virulence determinant of Group A Streptococcus (GAS). PAM contains irregularly spaced heptad repeats, particularly within its C‐ and D‐domains. Our recent cryo‐EM structure of PAM from GAS strain AP53 (PAMAP53) revealed that these repeats do not favor coiled‐coil formation, but instead
Olawole Ayinuola   +3 more
wiley   +1 more source

A study of empyema thoracis and role of intrapleural streptokinase in its management

open access: yesBMC Infectious Diseases, 2004
Background Clinical spectrum, microbiology and outcome of empyema thoracis are changing. Intrapleural instillation of fibrinolytic agents is being increasingly used for management of empyema thoracis.
Dey AB   +5 more
doaj   +1 more source

Dose de-escalation of intrapleural tissue plasminogen activator therapy for pleural infection. The alteplase dose assessment for Pleural infection Therapy project [PDF]

open access: yes, 2017
Rationale: Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10 mg and DNase 5 mg administered twice daily has been shown in randomized and open-label studies to successfully manage over 90% of patients with pleural infection ...
Bintcliffe, Oliver   +10 more
core   +1 more source

Studies on Specificity of Streptokinase.

open access: yesExperimental Biology and Medicine, 1958
Summary1. Ability of SK to activate the fibrinolytic system in plasma or euglobulin fractions of various animal species has been studied. 2. Human, cat, dog and rabbit plasminogens were readily activated by SK. Pig, horse and cow plasminogens were much less readily activated.
James J. Hagan, Frank B. Ablondi
openaire   +3 more sources

Streptokinase production from Streptococcus dysgalactiae subsp. equisimilis SK-6 in the presence of surfactants, growth factors and trace elements

open access: yes3 Biotech, 2014
Streptokinase is an extracellular protein secreted by various strains of streptococci and is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction.
Shilpi Bhardwaj, J. Angayarkanni
semanticscholar   +1 more source

Cerebral Venous Thrombosis:Current Status and Challenges

open access: yesBrain and Behavior, Volume 15, Issue 9, September 2025.
Our review introduces treatment strategies for short‐term, long‐term, and permanent CVT risk factors, focusing on anticoagulant selection and treatment duration. We also discuss the current status of endovascular therapy for CVT, noting that it remains a challenge due to limited evidence, and more research is needed to optimize this approach.
Wenbo Zuo   +5 more
wiley   +1 more source

Acute myocardial infarction associated with right bundle branch block and changeable trifascicular block: a case report

open access: yesJournal of Acute Disease, 2019
Rationale: Acute myocardial infarction in the presence of right bundle branch block. Patient concerns: A 70-year-old, male heavy smoker presented with angina and hypertension.
Yasser Mohammed Hassanain Elsayed
doaj   +1 more source

Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy [PDF]

open access: yes, 2010
Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Babu, Suresh   +2 more
core   +1 more source

Various aspects of thrombolysis and fibrinolysis [PDF]

open access: yes, 1969
The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core   +1 more source

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