Results 51 to 60 of about 27,568 (254)

Safety and efficacy of enoxaparin versus unfractionated heparins in conservatively managed patients with acute coronary syndrome: a systematic review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Aim Guidelines recommend initial anticoagulant management of acute coronary syndrome (ACS) with low molecular weight heparin (LMWH) such as enoxaparin or unfractionated heparin (UFH). Systematic reviews evaluate early trials in the context of multiple other medications or during percutaneous coronary intervention (PCI) only.
Krishna Doshi, Mark Jones, Laetitia Hattingh   +2 more
wiley   +1 more source

Streptokinase resistance: when might streptokinase administration be ineffective? [PDF]

Heart, 1992
(a) To develop an assay for streptokinase resistance. (b) To determine the prevalence of streptokinase resistance in patients presenting with acute myocardial infarction for the first time. (c) To determine the prevalence of streptokinase resistance in patients after exposure to streptokinase or streptococcal infection.Open, prospective.30 healthy ...
Trevor Baglin, Buchalter Mb, Luddington Rj, P. L. Weissberg, G Suntharalingam, Jennings I, C Hart, Jacobson Sk, Ronjon Chakraverty   +8 more
openaire   +3 more sources

Common Practice of Percutaneous Drainage in Necrotising Pancreatitis—A Multicentre Retrospective Study (DRACULA)

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims Acute necrotising pancreatitis carries high mortality, especially if infected necrosis occurs. While percutaneous drainage may be required when internal drainage is not feasible, reliable guidelines for managing percutaneous drains are lacking.
Marlies Vornhülz, Simon Sirtl, Yujun Xu, Sarah Klauss, Elisabeth Orgler‐Gasche, Mihailo Bezmarevic, Milan Jovanovic, Claudio Ricci, Michael Fernandez Y. Viesca, Marianna Arvanitakis, Amer Hadi, August Pilegaard Prahm, Davide Di Mauro, Dietrich A. Ruess, Carola Focke, Fabienne Bender, Jacob Hamm, Christoph Ammer‐Herrmenau, Tiago Cúrdia Gonçalves, João Carlos Gonçalves, Lenika Calavrezos, Mara Götz, Simon Stoerzer, Moritz Schmelzle, Łukasz Nawacki, Carlos Condori, Max Seitzinger, Julian Seelig, Serge Chooklin, Serhii Chuklin, Sebastian Rasch, Veit Phillip, Sanjay Pandanaboyana, Rami Aljaberi, Matta Kuzman, Christian Meinhardt, Belén González de la Higuera Carnicer, David Ruiz‐Clavijo García, Bálint Eross, Peter Hegyi, Nizar Kerbazh, Tudor Voicu Moga, Katarzyna Pawlak, Natalia Calo, Kareem Khalaf, Maximilian Brunner, Lucas Schulte, Alexander Kleger, María Lourdes Ruiz Rebollo, Max Seidensticker, Moritz Wildgruber, Ulrich Mansmann, Hans Stubbe, Julia Mayerle, Georg Beyer, the DRACULA study group: Laszlo Czako, Valentina Ratkajec   +56 more
wiley   +1 more source

Synthesis of human plasminogen by the liver [PDF]

, 1980
Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.
Alper, CA, Levey, R, Marcus, D, Raum, D, Starzl, TE, Taylor, PD   +5 more
core   +1 more source

Molecular Characterization of the Group A Streptococcus Virulence‐Regulatory System FasBCAX

Molecular Microbiology, EarlyView.
The Fas system of the group A Streptococcus is comprised of three proteins (FasBCA) and a small regulatory RNA (FasX), and it represses adhesin production while also promoting the production of the spreading factor streptokinase. Here, we analyze the Fas proteins to assess how they positively regulate FasX production.
Sushila Baral, Roshika Roshika, Clay P. Renshaw, Ameya Singh, Ashna Prabhu, Ira Jain, Rebekah Woolsey, David Quilici, Yftah Tal‐Gan, Paul Sumby   +9 more
wiley   +1 more source

Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes. [PDF]

PLoS ONE, 2017
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish, Craig Thelwell, Colin Longstaff   +2 more
doaj   +1 more source

Various aspects of thrombolysis and fibrinolysis [PDF]

, 1969
The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core   +1 more source

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

MedComm, Volume 6, Issue 10, October 2025.
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu, Yiwen Li, Qian Xu, Wenting Wang, Yanfei Liu, Yue Liu   +5 more
wiley   +1 more source

Postoperative care in finger replantation. Our case-load and review of the literature [PDF]

, 2015
OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc, Cigna, Emanuele, LO TORTO, Federico, Maruccia, Michele, Ribuffo, Diego, Ruggieri, M, Zaccheddu, F   +6 more
core  

Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty [PDF]

, 1988
A randomised trial of 367 patients with acute myocardial infarction was performed to determine whether an invasive strategy combining thrombolysis with recombinant tissue-type plasminogen activator (rTPA), heparin, and acetylsalicylic acid, and immediate
Arnold, A.E.R. (Alfred), Betriu, A., Bono, D.P. (David) de, Col, J.J. (Jacques), Dougherty, F.C., Essen, R. von, Lambertz, H., Lubsen, J. (Jacob), Meier, B. (Bernard), Michel, P.L., Raynaud, P. (Philippe), Rutsch, W.R. (Wolfgang), Sanz, G.A., Schmidt, W., Serruys, P.W.J.C. (Patrick), Simoons, M.L. (Maarten), Thery, C., Uebis, R., Vahanian, A.S. (Alec), Verstraete, M. (Marc), Werf, F.J.J. (Frans) van de, Willems, G.M. (George), Wood, D.   +22 more
core   +1 more source