Results 91 to 100 of about 737,951 (291)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

DETERMINATION OF PATHOGEN RESISTANCE TO STREPTOMYCIN

Cluj Veterinary Journal, 2009
This research was made in order to emphasize the actual incindence of the sensibility of various bacterial pathogens to streptomycin. The pathogens were identified as belonging to Staphylococcus, Escherichia, Citrobacter, Enterobacter, Klebsiella,
Anca CHEREJI, Rareş CHEREJI
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Induction of streptomycin resistance in the wild tomato Lycopersicon peruvianum [PDF]

, 1990
A protoplast mutagenesis and cell selection system was used for the isolation of streptomycin resistant Lycopersicon peruvianum colonies. Protoplasts were treated with the mutagen N-nitroso-methylurea and could be regenerated into fertile plants ...
Akerboom, M.J.E.,, Jansen, C.E., Hille, J., Snel, E.A.M., Nijkamp, H.J.J., Jansen, C.E.,, Snel, E.A.M.,, Nijkamp, H.J.J.,, Akerboom, M.J.E., Hille, J.,   +9 more
core   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The Effects of Local Streptomycin/lidocaine Injections on Treatment of Carbamazepine Resistant Trigeminal Neuralgia

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Trigeminal neuralgia is the most common type of facial neuralgia. The pain would easily affect the quality of life according to its acute and severe nature. Treatment modalities include pharmacotherapy, microvascular decompression,
Amir Hooman Sadr Haghighi, Seyed ahmad Arta, Mohammad Hossein Ahangar Atashi, Tannaz Abdollahzadeh Baghaei   +3 more
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Tuberculose resistente: revisão molecular

Revista de Saúde Pública
O progresso na compreensão dos mecanismos de resistência aos fármacos usados no tratamento da tuberculose tem permitido o desenvolvimento de novos métodos para a detecção da tuberculose resistente.
Maria Lúcia Rosa Rossetti, Andréia Rosane de Moura Valim, Márcia Susana Nunes Silva, Vívian Sumnienski Rodrigues   +3 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Etymologia: Streptomycin

Emerging Infectious Diseases, 2019
Ronnie Henry
doaj   +1 more source