Beneficial effects of protocatechuic acid on diabetic retinopathy in streptozocin-induced diabetic rats [PDF]
International Journal of Ophthalmology, 2023 AIM: To determine the effects of protocatechuic acid (PCA) on streptozocin-induced diabetic retinopathy (DR) in rats. METHODS: Wistar rats were given a 50 mg/kg intraperitoneal injection of streptozocin to induce diabetes.
Ling Wan +3 more
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Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice [PDF]
Frontiers in Nutrition, 2022 ObjectiveGiven that the prevalence rate of type 2 diabetes mellitus (T2DM) continues to increase, it is important to find an effective method to prevent or treat this disease. Previous studies have shown that dietary intervention with a slowly digestible
Yu-Zhong Chen +11 more
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Cinnamaldehyde attenuates streptozocin-induced diabetic osteoporosis in a rat model by modulating netrin-1/DCC-UNC5B signal transduction [PDF]
Frontiers in PharmacologyBackground: Cinnamaldehyde (CMD) is a major functional component of Cinnamomum verum and has shown treatment effects against diverse bone diseases. This study aimed to assess the anti-diabetic osteoporosis (DOP) potential of diabetes mellitus (DM) and to
Songjie Ji +7 more
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Crystal Structure of Streptozocin
Analytical Sciences: X-ray Structure Analysis Online, 2003 The crystal belongs to space group P212121, and the cell dimensions are a = 8.5300(5), b = 11.4516(9) and c = 23.893(1)A. The final R value is 0.047. There are two crystallographically independent molecules in an asymmetric unit. The pyranose rings in both molecules take chair conformations. The nitrosourea moieties are planar.
Masayuki Haramura +3 more
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Type 2 Diabetes Mellitus Exacerbates Brain Injury After Status Epilepticus in Rats [PDF]
Brain SciencesBackground: Clinical and experimental evidence suggests comorbidity between diabetes mellitus (DM) and epilepsy, including a higher incidence of status epilepticus (SE). However, the association between Type 2 Diabetes Mellitus (T2DM) and epilepsy is not
Carol-Victoria Mérida-Portilla +5 more
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Hypoglycemic episodes exacerbate skeletal muscle insulin resistance in type 2 diabetes mellitus [PDF]
Journal of Advanced Pharmaceutical Technology & ResearchTo date, the specific impact of hypoglycemia on insulin resistance in skeletal muscle is unclear. This study aimed to investigate the correlation between hypoglycemia in individuals with Type 2 Diabetes Mellitus by assessing peroxisome proliferator ...
Hendra Zufry +4 more
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The Effects of Methanolic Extract of Prosopis Farcta Seed on Blood Glucose in Streptozocin Induced Diabetic Rats [PDF]
Journal of Kerman University of Medical Sciences, 2017 Background: Previous studies have shown the beneficial effects of Prosopis species in the treatment of diabetes in traditional medicine. This study was performed to evaluate the antihyperglycemic effects of Prosopis farcta (P.farcta) in streptozocin ...
Sahel Heidar Lashkari Heidar Lashkari +3 more
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Streptozocin–Doxorubicin, Streptozocin–Fluorouracil, or Chlorozotocin in the Treatment of Advanced Islet-Cell Carcinoma [PDF]
New England Journal of Medicine, 1992 The combination of streptozocin and fluorouracil has become the standard therapy for advanced islet-cell carcinoma. However, doxorubicin has also been shown to be active against this type of tumor, as has chlorozotocin, a drug that is structurally similar to streptozocin but less frequently causes vomiting.In this multicenter trial, we randomly ...
Charles G. Moertel +4 more
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Probiotic preserving extract supplementation as a novel attitude in managing diabetes mellitus [PDF]
BMC Complementary Medicine and TherapiesType 2 diabetes is a metabolic disease characterized by insulin resistance. This study evaluated the effects of oral supplementation with a lyophilized probiotic extract (LPE) of Lactobacillus acidophilus and Lactobacillus plantarum on insulin resistance
Afrooz Saadatzadeh +5 more
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VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway
European Journal of Histochemistry, 2022 Diabetic retinopathy (DR) is a common microvascular complication in patients with diabetes mellitus. DR is caused by chronic hyperglycemia and is characterized by progressive loss of vision because of damage to the retinal microvasculature.
Meiying Zhang +10 more
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